MARKET PULSE-Prosensa, Verenium, Cyclacel, Apple, Microsoft

Reuters - UK Focus

(For more market insights, including options activity, click on ; for the Day Ahead newsletter http://link.reuters.com/mex49s; for the Morning News Call newsletter, http://link.reuters.com/nex49s)

Sept 20 (Reuters) - Wall Street was set for a slightly loweropen on Friday following comments by a senior Federal Reserveofficial who said that the U.S. central bank's stimulus effortscould be scaled back from as early as October. S&P 500 futures fell 1.5 points, Dow Jones (DJI: ^DJI - news) industrial average futures fell 19 points, while Nasdaq 100 futures added3.25 points. Some U.S. stocks to watch on Friday:

** PROSENSA, Thursday close $24.00, down 75 pctpremarket

** SAREPTA THERAPEUTICS (NasdaqGM: SRPT - news) , Thursday close $36.69,down 8 pct premarket

An experimental drug for Duchenne muscular dystrophy fromGlaxoSmithKline (Other OTC: GLAXF - news) and Prosensa failed to meet its goal in alate-stage clinical trial, the companies said on Friday. Thedrug, drisapersen, did not show a statistically significantimprovement in the distance that patients could walk in sixminutes compared to a placebo in the Phase three test.

Shares of rival Sarepta, which is also making a drug forDuchenne muscular dystrophy, also fell 8 percent in premarkettrade.

** VERENIUM CORP, Thursday close $2.51, up 60 pctpremarket

The company announced that it has entered into a definitivemerger agreement with BASF Corporation, a chemicals company,under which BASF will commence a cash tender offer for all ofthe outstanding shares of Verenium's common stock. Based on alloutstanding shares and including all net financial liabilities,the enterprise value would be approximately USD62 million(approximately EUR 48 million).

** MICROSOFT CORP, Thursday close $33.64

Microsoft Chief Executive Steve Ballmer has made animpassioned plea to investors to support his vision of theworld's largest software company as a unified devices andservices powerhouse in his swan song before Wall Street.

** APPLE INC (NasdaqGS: AAPL - news) , Thursday close $472.30, up 1.4 pctpremarket

Apple's new iPhones 5C and 5S will be available for purchaseat Apple retail stores from today in the U.S., Australia,Canada, China, France, Germany, Hong Kong, Japan, Puerto Rico,Singapore and the U.K. "We believe Apple will sell 6-6.5 millionnew iPhones this weekend," Cantor Fitzgerald analyst Brian Whitesaid in a note.

** CYCLACEL PHARMACEUTICALS INC (NasdaqGM: CYCC - news) , Thursday close$3.80, up 40 pct premarket

The drugmaker said on Thursday that updated data from aclinical study showed its experimental product, sapacitabine,has activity against a majority of ovarian cancer samples takenfrom patients, including resistant tumors. The drug is currentlybeing tested in late-stage studies as a as front-line treatmentfor acute myeloid leukemia in the elderly.

** GOODYEAR TIRE & RUBBER CO, Thursday close $22.23,up 5 pct premarket

The U.S. tire maker on Friday affirmed its profit forecastfor the year and reinstated a common stock dividend. The companyalso announced a $100 million share buyback program. It said theprogram was intended to offset new shares issues under stockcompensation programs.

** TIBCO SOFTWARE INC (NasdaqGS: TIBX - news) , Thursday close $25.25, up 7pct after market

The company on Thursday said its contract pipeline for thenext year was robust as customers become more willing to spendon large deals, and the business software maker added that itsAmericas business was "back to strength".

At least five brokerages, including Barclays (LSE: BARC.L - news) and JP Morgan (Other OTC: JPYYL - news) ,raised their price targets on Tibco's stock on Friday.Susquehanna upgraded the stock to "positive" from "neutral".

** FIREEYE INC, IPO price $20.00

The cybersecurity company FireEye priced its initial publicoffering of about 15.2 million shares above its proposed pricerange. The IPO price values FireEye at about $2.3 billion. Thecompany raised about $304 million from the offering. All theshares in the IPO were sold by the company.

** ROCKET FUEL INC, IPO price $29.00

The advertising technology company's initial public offeringwas priced at the higher end of its proposed price range, anunderwriter told Reuters. The company raised $116 million fromthe offering of about 4 million shares. All the shares in theIPO were sold by Rocket Fuel.

** CLUBCORP HOLDINGS INC IPO price $14.00

The golf club operator offered 18 million shares in its IPOand would receive net proceeds of about $168.8 million.

** SOLARWINDS INC (NYSE: SWI - news) , Thursday close $39.12

Goldman Sachs (NYSE: GS-PB - news) downgraded the stock to sell from neutral,according to the website theflyonthewall.com.

** DARDEN RESTAURANTS INC (NYSE: DRI - news) , Thursday close $49.30,down 5 pct premarket

The restaurant operator reported a lower quarterly profitand higher sales on Friday and said President and ChiefOperating Officer Drew Madsen would retire at the end of thisquarter.

** TITAN INTERNATIONAL INC (NYSE: TWI - news) , Thursday close $16.11

The equipment parts supplier announced that it waswithdrawing its fiscal 2013 guidance relating to revenue andEBITDA. It is unlikely to issue any updates until its fiscal2014 guidance on January 2014, it said.

** KAR AUCTION SERVICES INC (NYSE: KAR - news) , Thursday close $28.27,down 3 pct premarket

The vehicle auction company announced an underwrittenoffering of 12 million shares by existing stockholder KARHoldings LLC.

** BALTIC TRADING LTD, Thursday close $5.10, down10 pct after market

The drybulk shipper on Thursday said it was offering itscommon shares to fund vessel acquisitions, working capital andother activities.

** NGL ENERGY PARTNERS LP (NYSE: NGL - news) , Thursday close $33.73,down 4 pct after market

The propane gas supplier on Thursday said it would offer 4.1million units in an offering. The proceeds from the sale will beused to repay debt, the company said.

** TOWERS WATSON CO, Thursday close $100.09

British insurance broker Jardine Lloyd Thompson Group Plc said it would acquire the reinsurance brokerage businessof Towers Watson Co for $250 million in cash.

** CINTAS CORP, Thursday close $50.89, up 3 pctafter market

The supplier of rental uniforms for corporates reported ahigher first-quarter profit, helped by higher sales acrosssegments, and raised its 2014 earnings outlook.

** JINKOSOLAR HOLDING CO LTD, Thursday close $16.48,up 3.7 pct premarket

The solar panel maker said on Thursday it would offer 3.8million American depositary shares (ADS) priced at $16.25 eachto expand its manufacturing capacity, develop solar projects andfund working capital.

** AK STEEL HOLDING CORP, Thursday close $4.40, down7.5 pct after market

The steel maker estimated a wider-than-expected loss for thethird quarter as production was hit by a mechanical failure atits Ohio facility, sending its shares down 7 percent inafter-market trading. The steelmaker said it expects to incur aloss of 22 cents to 27 cents per share. Analysts were expectinga loss of 11 cents per share, according to Thomson ReutersI/B/E/S.

** TRANSCEPT PHARMACEUTICALS INC (NasdaqGM: TSPT - news) , Thursday close$3.76, up 4 pct after market

The drugmaker's largest shareholder, Roumell AssetManagement, said on Thursday it believed that Retrophin Inc (Other OTC: RTRX - news) 's offer to buy Transcept at $4 per share was "woefullyinadequate," and urged the company to launch an open auctionprocess to solicit interest from additional parties.

The investor further said it had been contacted by manyshareholders who expressed their "deep dissatisfaction" withTranscept's management team. (http://r.reuters.com/mej33v)

** HUNTSMAN CORP, Thursday close $20.38, up 2 pctafter market

BofA Merrill Lynch on Thursday upgraded the chemical maker'sstock to "buy" from "neutral", according to theflyonthewall.com.The rating change comes two days after Huntsman said it wasbuying Rockwood Holdings Inc's titanium dioxide pigmentsbusiness for $1.1 billion. Huntsman expects demand for the whitepigment, used in paint and many consumer goods, to recover incoming quarters, partly due to a recovery in the housing andautomobile industries in North America.

** NAVIOS MARITIME PARTNERS LP, $14.93, down 6.6 pctpremarket

The shipping company said it plans to offer 5 million commonunits in a public offering. Navios expects to use the netproceeds to fund its fleet expansion and for general partnershippurposes.

** VALERO ENERGY CORP, Thursday close $34.73, up 1pct after market

Valero Energy Partners LP filed with U.S. regulators onThursday to raise up to $345 million in an initial publicoffering of common units. The company was formed by ValeroEnergy Corp to operate pipelines and terminals for thetransportation of crude oil and refined petroleum products.

** TATA MOTORS LTD , Thursday close $27.67,down 2.5 pct premarket

Tata Motors, India's largest automaker by revenue, islooking to raise prices by 1 percent-1.5 percent across itsrange of commercial and passenger vehicles, following similarmoves by rival carmakers.

** FOX FACTORY HOLDING CORP, Thursday close $18.38,down 3 pct after market

The maker of suspension products used on mountain bikes andall-terrain vehicles reported second-quarter earnings lower thananalysts' estimates. The company forecast full-year 2013earnings to be 61 to 67 cents per share and revenue to be $264million to $270 million.

** GOLDMAN SACHS, Thursday close $167.78

The company was hit by a clerical error at the New YorkFederal Reserve that left the bank without any of thethree-month Treasury bills it ordered at a debt auction, theFinancial Times reported, citing people familiar with thematter.

** GLAXOSMITHKLINE PLC , Thursday close$50.27

** THERAVANCE INC (NasdaqGS: THRX - news) , Thursday close $41.20

GlaxoSmithKline and Theravance's new inhaled lung drugRelvar has been approved in Japan, a day after winning apositive recommendation in Europe.

** SANOFI SA , Thursday close $50.84

Sanofi (NasdaqGM: GCVRZ - news) has reached a $40 million settlement of a U.S.lawsuit accusing the French drugmaker of misleading investorsabout the safety of a weight loss pill that a U.S. regulatorypanel linked to suicidal thoughts.

** WALT DISNEY CO, Thursday close $65.72

The Walt Disney and Jerry Bruckheimer, the producer behindthe blockbuster "Pirates of the Caribbean" franchise and thesummer flop "The Lone Ranger," will end their long-running filmdeal next year, the media company announced on Thursday. (Compiled by Varun Aggarwal)

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