How might immigration reform affect Rubio in 2016?

The Washington Examiner's Byron York reflects on John McCain's presidential run in 2008 and how the issue of immigration reform affected his standing with the conservative base. (Surprise: It stank.)

But will Florida Sen. Marco Rubio suffer the same fate?

How might immigration reform affect Rubio in 2016?
How might immigration reform affect Rubio in 2016?

Surely Rubio has more in common with the base than McCain ever did, but immigration is a hot-button issue -- could it bring down an entire potential campaign?

It just might, York notes:

Over the weekend I emailed a number of Iowa conservatives to ask them a few general questions about the GOP field. I didn't mention immigration or any other issue; I just wanted their thoughts. What I got back, as far as Rubio was concerned, was all about immigration, and nearly all negative. [...]

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