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    Scientists pause research with lab-bred bird flu

    WASHINGTON (AP) — Scientists who created easier-to-spread versions of the deadly bird flu said Friday they are temporarily halting more research, as international specialists debate what should happen next.

    Researchers from leading flu laboratories around the world signed onto the voluntary moratorium, published Friday in the journals Science and Nature.

    What the scientists called a "pause" comes amid fierce controversy over how to handle research that is high-risk but potentially could bring a big payoff. Two labs — at Erasmus University in the Netherlands and the University of Wisconsin-Madison — created the new viruses while studying how bird flu might mutate to become a bigger threat to people.

    The U.S. government funded the work but last month urged the teams not to publicly reveal the exact formula so that would-be bioterrorists couldn't copy it. Critics also worried a lab accident might allow the strains to escape. The researchers reluctantly agreed not to publish all the details as long as the government set up a system to provide them to legitimate scientists who really need to know. The National Institutes of Health is creating such a system.

    "We recognize that we and the rest of the scientific community need to clearly explain the benefits of this important research and the measures taken to minimize its possible risks," lead researchers Ron Fouchier of Erasmus and Yoshihiro Kawaoka of Wisconsin wrote Friday in the letter. They were joined by nearly three dozen other flu researchers.

    They called for a public international meeting to debate how to learn from the work, safely. And they agreed to hold off on additional research with the existing lab-bred strains or that leads to any new ones for 60 days.

    A U.S. official praised the development.

    The moratorium "is a really good idea, because a lot of very important issues are at hand," said Dr. Anthony Fauci, director of the NIH's National Institute of Allergy and Infectious Diseases, who expects most flu researchers doing such work to sign on. "There aren't a lot of people who are doing that, I can assure you."

    The U.S. also wants international input; researchers are talking with the World Health Organization.

    Today, the so-called H5N1 bird flu only occasionally infects people, mostly those who have close contact with sick poultry. But when it does, it is highly lethal. The lab-bred H5N1 strains were a surprise because they showed it was easier than previously thought for the virus to mutate in a way that lets it spread easily between at least some mammals — in this case, ferrets.

     
    • Larry  •  Mililani Town, Hawaii  •  4 mths ago
      Here comes CAPT Tripps. "He's a righteous man" Stephen King, The Stand.
    • Yahoo  •  4 mths ago
      Medical/agricultural studies over the years have revealed the ROOT cause of swine and bird flu to be the overcrowding and abuse of farm animals in factory farm operations where animals are forced to continuously stand in their own waste which produces ammonia and other corrosive gases which burns away their mucus membranes making their respiratory tracts highly susceptible to various viral and bacterial infections. This in turn....of course, requires farmers to dose these animals with high doses of antibiotics and other drugs which breeds antibiotic resistance that can then be transferred to human hosts. Other factors which weakens these animals immune systems include being fed feeds which they were not evolved to eat, being fed multiple growth hormones and being given multiple antibiotics to promote faster growth in conjunction with growth hormones. The close confinement/overcrowding of these animals causes them to attack/bite, bleed, defecate, urinate, vomit, cough, sneeze on one another. In order to control this aggression/open wounds, farmers cut off the birds beaks and cut off the pigs tails etc. instead of giving these animals more space/access to outdooor pasture. Sunlight is known to kill many viruses and bacteria. These conditions accelerate the speed in which viruses like swine and bird flu mutate and proliferate. More vaccines and antibiotics will only allow these viruses, and the cruel factory farming conditions which allows them to proliferate, to continue unabated, requiring more vaccines to control newly evolved viruses and bacteria which have become immune to present antibiotics and vaccines. The long term solution to these plagues is to allow domestic animals access to open pasture and grazing/being fed foods they were evolved to eat. Sunlight kills many deadly/disease carrying viruses and bacteria. In these open-air/free ranging and more SANITARY conditions farmers will no longer be required to use expensive drugs to control disease. Growth hormone usage should be discontinued in favor of sustainable/free ranging farming practices which strengthen the immune systems of domestic animals. These animals took millions of years to evolve on earth, we should treat them with respect/caring. It seems that our abuse and commodification of these animals has now given them the power to kill US. From the bible's book of Revelation Chapter 6:...."And I looked, and behold a pale horse: and his name that sat on him was Death, and Hell followed with him. And power was given unto them over the fourth part of the earth, to kill with sword, and with hunger, and with death, AND WITH THE BEASTS OF THE EARTH".
    • Cheep-O  •  4 mths ago
      Watch "Influenza 1918" on American Experience on PBS online if you want to see what our not too distant history shows us about pandemics. Scary stuff.
      • Cheep-O 4 mths ago
        That flu killed over 600,000 Americans.

        Here's a little excerpt from it the show:

        "Meanwhile, returning American troops were bringing the flu back home. First hundreds, then thousands of soldiers were lining up outside infirmaries and hospitals at army bases across the country, falling ill with a swiftness that defied belief. Dr. Victor Vaughan, Surgeon General of the Army, was stunned by what he saw at Camp Devens just outside of Boston. “Every bed is full, yet others crowd in,” he wrote. “The faces wear a bluish cast; a cough brings up the blood-stained sputum. In the morning, the dead bodies are stacked about the morgue like cordwood.” On the day Vaughan arrived, 63 men died at Camp Devens.

        In September, the disease spread to the civilian population. It moved swiftly down the eastern seaboard to New York, Philadelphia, and beyond. Anna Milani remembers sitting on her front step one day: “Diagonally across from us a fifteen-year-old girl was just buried. Toward evening, we heard a lot of screaming going on. In that same house, a little eighteen-month-old baby passed away.” That month, 12,000 Americans died of influenza.

        It was a flu unlike any other. People could be healthy in the morning and dead by nightfall. Others died more slowly, suffocating from the buildup of liquid in their lungs.

        Thanks to advances in microbiology, researchers had developed vaccines for many bacterial diseases: smallpox, anthrax, rabies, diphtheria, meningitis. But doctors were helpless to stop the influenza of 1918. Though they knew the disease spread through the air, medical researchers were unable to see the tiny virus through microscopes of the time and incorrectly identified its cause as a bacteria. Vaccines they developed didn’t work; the virus was too small, too elusive.

        With medical science powerless, many people turned to folk remedies: garlic, camphor balls, kerosene on sugar, boneset tea. Public health officials distributed masks, closed schools; laws forbade spitting on the streets. Nothing worked. The war was at cross-purposes with the epidemic: the war effort brought people into the streets for rallies and bond drives. They coughed on each other, infected each other. Soldiers traveled in crowded transport ships. The disease spread everywhere.

        October saw the epidemic’s full horror: more than 195,000 people died in America alone. There was a nationwide shortage of caskets. In Philadelphia, the dead were left in gutters and stacked in caskets on front porches. Trucks drove the city streets, picking up the caskets and corpses. People hid indoors, afraid to interact with their friends and neighbors."
      • True speach Article one p ... 4 mths ago
        Our troops spread it around the world, it started here in the mid west at an army barracks. Lewarn the truth before spreading propaganda
      • True speach Article one p ... 4 mths ago
        I did a report on it in Bio-ethics class. We dug up bodies from church yard graves in the permafrost to culture it. So we have the same strain again, and we found out through PCR analysis where it started. What we found was that it turned Peoples organs and such into some kind of black goo. Not good, and now we decided to make it spread even easier. How insane is that?
    • uuuubstrds  •  Fayetteville, North Carolina  •  4 mths ago
      and people think IRANS THE THREAT.
    • Rick  •  4 mths ago
      Who the hell would "legitimately need to know" how to create an even more deadly strain of bird flu?!
    • michaelt  •  Oak Ridge, Tennessee  •  4 mths ago
      They are playing with a fire that could burn through the human race. That now makes this a Level 4 Bio-Hazard that has a motatilty rate (MA) that is unknown. Ebola has a MR of 50 to 90%. That means that depending on what strain....it kills 50 to 90% of those infected. Read HOT ZONE by Richard Preston....it will show just how scared you should be of this. This Bird-Flu strain needs to be destroyed now and forever.
      • someone 4 mths ago
        Good book. read it in high school
      • Eric 4 mths ago
        Overreaction. For one, diseases with high MR burn out quickly. For that reason, diseases with the highest death tolls of all time have relatively low MR.
      • steven h 4 mths ago
        Doesn't matter. If it kills 100 million, it still kills 100 million. Short time makes it harder to find a vaccine
    • Menace  •  4 mths ago
      Mankind will be the creator of its own demise, you dont have to worry about some natural disaster or the hand of god fly swatting us, we're natural born killers.
      • SUMGUY2006 4 mths ago
        Is that why we've defied "Nature" and spread like wildfire? Every year we live longer, and they're are more of us. Of course eventually our success may catch up with us in a big way.
    • deCivilis  •  4 mths ago
      28 days later...
    • AdrianoF  •  4 mths ago
      Never open Pandora's box.
    • Fooki  •  4 mths ago
      Debate over- destroy it. All samples and formulas -just destroy it or it will come back even more mutated and more easily transmitted than what you have created in the labs. It's what viruses do - they mutate to survive and you just sped up their so called evolution... Destroy it now.
    • Abolish the IRS  •  Fremont, California  •  4 mths ago
      ...and you still think AIDS came from nature...really???
    • RHill  •  4 mths ago
      Other than a bio-weapon, what possible good could come from "creating" an easier-to-spread version of a deadly virus? That's crazy ... how stupid do they think we are?
    • Dixie  •  4 mths ago
      The U.S. government funded the work........

      Perfect to use on people around the world including Americans.
    • Androsynth  •  4 mths ago
      "as international specialists debate what should happen next."
      Here's what should happen next: They stop working on that bloody apocalypse virus and destroy all the associated lab/research materials so that NO ONE can replicate the work in progress. One thing is to work on a theoretical model on a contagion and quite another is to actually try to mutate such a potentially catastrophic virus on purpose in a lab. Like any nation is responsible enough to handle this kind of work. Bloody pikers.
    • True speach Article one p ...  •  Santa Clara, California  •  4 mths ago
      I did a report on it in Bio-ethics class. We dug up bodies from church yard graves in the permafrost to culture it. So we have the same strain again, and we found out through PCR analysis where it started. What we found was that it turned Peoples organs and such into some kind of black goo. Not good, and now we decided to make it spread even easier. How insane is that?
    • 1  •  Santa Cruz, California  •  4 mths ago
      Do we really need to be doing this?
    • Fooki  •  4 mths ago
      "probably one of the most dangerous viruses you can make". (Ron Fouchier) According to the FAO Avian Influenza Disease Emergency Situation Update, H5N1 pathogenicity is continuing to gradually rise in endemic areas, but the avian influenza disease situation in farmed birds is being held in check by vaccination. That means it's already getting worse and we just helped it along tenfold... IT Will Return Without Our Assistance. Knowledge is a good thing and even a little can be very dangerous. Knowledge without character is unacceptable. Knowledge demands responsibility.
    • Amathiusm  •  Los Angeles, California  •  4 mths ago
      Anyone who does not have sufficient intelligence to address our worlds problems will become extinct anyway. Just look how inefficient current governments are - I mean 95% of all resources in 2% of peoples hands? really? Real effective management of resources there.

      Trillions on defense and pennies to scientific research? Scientists have created our world and yet are marginalized. Scientists should become far more politically active and far more militant. Handing over such powerful knowledge or putting a halt to it? As a biology student I know for a fact that even immortality is not out of reach with enough knowledge in this field.

      Why should scientists "Advance mankind" for free? and be at the behest of intellectual mediocrities / Liars AKA Politicians/CEO's ? Do we not have a duty to ensure the survival of our species? If its clear current policies wont work etc. should we not use all means at our disposal to ensure those policies end and ones based on scientific fact are used? Further why should we give evolutionary advantages to organisms which would go extinct without our intervention? The knowledge todo the things in this article and more are highly specialized adaptations inferring a tremendous evolutionary advantage to those that develop them. Why should we hand these advantages out for free rather than let natural selection take its course?

      Modern scientific thought seems backasswards at best.
    • Horns  •  Austin, Texas  •  4 mths ago
      just keep messing around with stuff. When 70% of the earth are zombies or dead dont say I didnt warn ya. oh and thanks for all this parking:P
    • Dr. Wu  •  Phoenix, Arizona  •  4 mths ago
      Didn't Steven King write a novel based on a lab releasing a biological agent? The Bruce Willis movie 12 Monkeys was about the same thing. All we need is one lunatic, scientist, or security guard to release a plague that will end human civilization. Why do we need this research again?
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