27 Stories, most recent news story added Wed Jul 8, 5:40 pm ET
A 36-year-old woman with rheumatoid arthritis who was receiving systemic immunotherapy died from disseminated histoplasmosis while participating in a gene-therapy trial of a tumor necrosis factor {alpha} antagonist delivered through an adeno-associated viral vector delivery system and administered by intraarticular injection.
In this issue of the Journal, Frank and colleagues present the case history and autopsy results of a widely publicized death in the summer of 2007 of a young woman ...
Researchers have identified a protein released by dying brain tumor cells that provides an effective way to gauge the effectiveness of a novel gene therapy treatment for brain cancer.
Researchers are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.
Vaseline, a known molecule from apples and a gene network encapsulated in algal gelatin are the components of a possible gene therapy which literally gets under the skin. An important part in this is played by phloretin, an antioxidant found in apples which makes cell walls more permeable and is used in cosmetics as an anti-wrinkle agent.
Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.Gregory Daniels, MD, PhD, assistant clinical professor of medicine at the UC San Diego School of Medicine and his co-workers are comparing the modified virus treatment, called OncoVEX GM-CSF, ...
Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.
Researchers hope herpes virus will kill cancer cells, bolster immune defense against disease.
Bennett bred a virus to carry the gene. Maguire injected it into a patient's eye. And there was light.
OK, that may be a little harsh, but it's the theme of this Discover article about how advances in gene therapy and genetic manipulation may ultimately change the concept of athletes.
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, July 1, 2009, in the JCI, including: "Clocking salt levels in the blood: a link between the circadian rhythm and salt balance"; "Defining immune pathways limiting gene therapy"; "Damaged kidneys want the protein CSF-1 to stimulate repair"; and "Developing blood ...
Gene therapy technique developed in animal model by Cedars-Sinai research team uses immune cells to attack glioblastoma multiformeA specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme.
A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma mulitforme.
A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma multiforme. The finding, reported in the July 1 issue of Clinical Cancer Research, paves the way for a Phase 1 clinical trial expected to begin in late 2009.
It is now possible to engineer tiny containers the size of a virus to deliver drugs and other materials with almost 100 percent efficiency to targeted cells in the bloodstream. According to a new Cornell study, the technique could one day be used to deliver vaccines, drugs or genetic material to treat cancer and blood and immunological disorders. (Gene Therapy online, June 25, 2009.)
University of Maryland School of Medicine researcher James Mixson has developed a gene therapy polymer that he is betting will have therapeutic siRNA-delivery applications.