Gene Therapy Brings New Muscle to Monkeys
MedicineNet.com - Fri Nov 13, 4:31 pm ETTitle: Gene Therapy Brings New Muscle to Monkeys Category: Health News Created: 11/12/2009 12:10:00 PM Last Editorial Review: 11/13/2009
Title: Gene Therapy Brings New Muscle to Monkeys Category: Health News Created: 11/12/2009 12:10:00 PM Last Editorial Review: 11/13/2009
A gene therapy treatment that stops the breakdown of muscle appeared safe in monkeys and may build up muscle, too, researchers reported on Wednesday.
A gene-therapy experiment in monkeys has shown the ability to boost muscle size and strength, giving hope to those looking for treatments for muscular dystrophy and other diseases that cause muscle loss and weakness.
Scientists are one step closer to clinical trials to test a gene delivery strategy to improve muscle mass and function in patients with certain degenerative muscle disorders.
Geneticist Mark Kay discusses the field's recent progress and the hurdles still left to overcome
Researchers at the California Institute of Technology have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. "Gene therapy in these models successfully attenuated the symptoms of Huntington's disease and increased life span," notes Paul Patterson, the ...
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength and no adverse effects, the Muscular Dystrophy Association (MDA) announced today. The findings could have implications particularly for injured and aging people worldwide; and for tens of millions experiencing ...
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
Researchers have successfully used gene therapy to increase monkeys' muscle strength. The team hopes to use the same treatment to help people with muscle-wasting diseases grow back their muscle strength.
Title: Gene Therapy for Fatal Brain Disorder 'Just the Beginning' Category: Health News Created: 11/5/2009 2:10:00 PM Last Editorial Review: 11/6/2009
CAMBRIDGE, Mass.----Genetix Pharmaceuticals, a leader in gene therapy of somatic stem cells, announced today the company’s clinical program to treat Adrenoleukodystrophy . The company is developing a gene therapy product in collaboration with Professor Patrick Aubourg and Doctor Nathalie Cartier of the National Institute of Health and Medical Research .
The Muscular Dystrophy Association is prepared to underwrite a clinical trial for a promising gene therapy that could preserve and strengthen muscle fibers in patients with neuromuscular diseases.
French scientists mixed gene therapy and bone marrow transplants in two boys to seemingly halt a brain disease that can kill by adolescence.
A breakthrough mix of stem cell and gene therapy halted a lethal brain-wasting illness in two young boys, and could prove effective against other genetic disorders, researchers reported Thursday.