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Using a gene-therapy delivery system developed in the laboratory of Inder Verma at the Salk Institute for Biological Studies, an international research team successfully treated two boys from Spain suffering from adrenoleukodystrophy (ALD), the rare, inherited disease that was the focus of the Hollywood film "Lorenzo's Oil." The genetic disorder, in which the fatty insulation of nerve cells ...
( The Mount Sinai Hospital / Mount Sinai School of Medicine ) Mount Sinai School of Medicine is one of 12 sites nationwide participating in the first Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease. The study is the first multicenter neurosurgical intervention in Alzheimer's research in the US.
Researchers are preparing for the first Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease. The study, the first multicenter neurosurgical intervention in Alzheimer's research in the U.S., utilizes a viral-based gene transfer system, CERE-110, that makes Nerve Growth Factor (NGF), a naturally occurring protein that helps maintain nerve cell survival in the brain.
Title: Gene Therapy Brings New Muscle to Monkeys Category: Health News Created: 11/12/2009 12:10:00 PM Last Editorial Review: 11/13/2009
AMSTERDAM, November 18 /PRNewswire-FirstCall/ -- - Glybera(R) Clinical Data Presented at Meeting of American Heart Association Amsterdam Molecular Therapeutics (EuroNext Amsterdam: AMT), a leader in the field of human gene therapy, today provides its non-audited business update in compliance with the EU transparency directive.
A gene therapy treatment that stops the breakdown of muscle appeared safe in monkeys and may build up muscle, too, researchers reported on Wednesday.
A gene-therapy experiment in monkeys has shown the ability to boost muscle size and strength, giving hope to those looking for treatments for muscular dystrophy and other diseases that cause muscle loss and weakness.
Scientists are one step closer to clinical trials to test a gene delivery strategy to improve muscle mass and function in patients with certain degenerative muscle disorders.
Nov. 15 (Bloomberg) -- A gene linked to breast cancer in 1 in 10 Jewish women may raise the risk of heart ailments, says a study in mice using gene therapy to improve cardiac function.
Geneticist Mark Kay discusses the field's recent progress and the hurdles still left to overcome
Researchers at the California Institute of Technology have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. "Gene therapy in these models successfully attenuated the symptoms of Huntington's disease and increased life span," notes Paul Patterson, the ...
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength and no adverse effects, the Muscular Dystrophy Association (MDA) announced today. The findings could have implications particularly for injured and aging people worldwide; and for tens of millions experiencing ...
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
Researchers have successfully used gene therapy to increase monkeys' muscle strength. The team hopes to use the same treatment to help people with muscle-wasting diseases grow back their muscle strength.
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