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Gene Therapy Stalls Development Of Huntington's Disease In Mice

Science Daily - Sun Nov 8, 10:25 pm ET

Researchers at the California Institute of Technology have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. "Gene therapy in these models successfully attenuated the symptoms of Huntington's disease and increased life span," notes Paul Patterson, the ...

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Gene Therapy for Fatal Brain Disorder 'Just the Beginning'
MedicineNet.com - Fri Nov 6, 4:27 pm ET
Title: Gene Therapy for Fatal Brain Disorder 'Just the Beginning' Category: Health News Created: 11/5/2009 2:10:00 PM Last Editorial Review: 11/6/2009
Gene Therapy Helps 2 Kids Suffering From Rare Brain Disease
Fox News - Fri Nov 6, 7:56 am ET
French scientists mixed gene therapy and bone marrow transplants in two boys to seemingly halt a brain disease that can kill by adolescence.
Gene therapy beats back brain wasting disease: study
AFP via Yahoo! News - Thu Nov 5, 6:09 pm ET
A breakthrough mix of stem cell and gene therapy halted a lethal brain-wasting illness in two young boys, and could prove effective against other genetic disorders, researchers reported Thursday.
Gene therapy makes major stride in 'Lorenzo's Oil' disease
Los Angeles Times - Fri Nov 6, 3:25 am ET
An experimental treatment stabilizes two boys with the rare, fatal degenerative disorder known as ALD. Researchers hail the findings, which come on the tail of other gene-therapy successes. In the third gene-therapy success of recent weeks, French researchers have arrested the progression of the rare and fatal degenerative disorder adrenoleukodystrophy, which was at the heart of the popular ...
New gene therapy halts 2 boys' rare brain disease
AP via Yahoo! News - Thu Nov 5, 5:12 pm ET
French scientists mixed gene therapy and bone marrow transplants in two boys to seemingly halt a brain disease that can kill by adolescence. The surprise ingredient: They disabled the HIV virus so it couldn't cause AIDS, and then used it to carry in the healthy new gene.
Scientists halt brain disease with new gene therapy
Reuters via Yahoo! News - Thu Nov 5, 3:36 pm ET
Scientists have managed to halt a rare and fatal brain disease with an experimental gene therapy technique using a deactivated version of the AIDS virus, a study published on Thursday showed.
After setbacks, small successes for gene therapy
Spartanburg Herald-Journal - Fri Nov 6, 5:22 pm ET
Published: Friday, November 6, 2009 at 5:15 a.m. Last Modified: Friday, November 6, 2009 at 5:15 a.m. Not long ago, gene therapy seemed troubled by insurmountable difficulties.
Gene Therapy Advance Saves Two Boys From Rare Brain Disease
Bloomberg - Thu Nov 5, 7:13 pm ET
Nov. 5 (Bloomberg) -- Two seven-year-old boys with a fatal brain disease who couldn’t get bone marrow transplants were saved by scientists whose gene therapy technique may let doctors treat other incurable disorders.
Rare Disease Treated Using Gene Therapy
NPR - Thu Nov 5, 3:07 pm ET
French scientists report that two boys treated with gene therapy for a rare but fatal genetic disease have shown improvements. These results mark a high point for the field of gene therapy. Shown here, the area of the brain that was treated.
Gene Therapy Halts Fatal Brain Disease
Wired News - Thu Nov 5, 2:25 pm ET
Doctors successfully use gene therapy to treat two boys with a fatal brain disease.
Gene Therapy Technique Slows Brain Disease ALD Featured In Movie 'Lorenzo's Oil'
Science Daily - Thu Nov 5, 5:31 pm ET
A strategy that combines gene therapy with blood stem cell therapy may be a useful tool for treating a fatal brain disease, French researchers have found.
Gene therapy success in severe brain disorder applauded by the STOP ALD Foundation
EurekAlert! - Thu Nov 5, 2:29 pm ET
( The StopALD Foundation ) First gene therapy success in boys with fatal brain disorder -- the Stop ALD Foundation, having spurred a successful European gene therapy trial, is now pressing to bring this therapy to the US. The foundation was started by families with children who have died or suffered from adrenoleukodystrophy, the disease highlighted in the movie Lorenzo's Oil. A report of the ...
Gene therapy technique slows brain disease
EurekAlert! - Thu Nov 5, 2:29 pm ET
A strategy that combines gene therapy with blood stem cell therapy may be a useful tool for treating a fatal brain disease, French researchers have found. These findings appear in the Nov. 6, 2009, issue of the journal Science, which is published by AAAS, the nonprofit science society.
Gene therapy transforms eyesight of 12 born with rare defect
Los Angeles Times - Wed Nov 4, 5:18 pm ET
A single injection in a patient's eye brings 'astounding' results. The findings may offer hope for those with macular degeneration and retinitis pigmentosa. Pennsylvania researchers using gene therapy have made significant improvements in vision in 12 patients with a rare inherited visual defect, a finding that suggests it may be possible to produce similar improvements in a much larger number ...
Brain disease treated by gene therapy
Scientific American - Fri Nov 6, 11:18 am ET
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