78 Stories, most recent news story added Fri Nov 13, 1:03 am ET
The standard treatment for venous leg ulcers, lower limb compression, takes up to six months to heal and is unsuccessful in 30 -70 percent of cases. The new treatment involved injecting venous leg ulcers with a non-replicating adenovirus that expresses platelet-derived growth factor-β (PDGF-β).
Researchers at the California Institute of Technology have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the development of Huntington's disease in a variety of mouse models. "Gene therapy in these models successfully attenuated the symptoms of Huntington's disease and increased life span," notes Paul Patterson, the ...
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength and no adverse effects, the Muscular Dystrophy Association (MDA) announced today. The findings could have implications particularly for injured and aging people worldwide; and for tens of millions experiencing ...
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.
Researchers have successfully used gene therapy to increase monkeys' muscle strength. The team hopes to use the same treatment to help people with muscle-wasting diseases grow back their muscle strength.
Title: Gene Therapy for Fatal Brain Disorder 'Just the Beginning' Category: Health News Created: 11/5/2009 2:10:00 PM Last Editorial Review: 11/6/2009
CAMBRIDGE, Mass.----Genetix Pharmaceuticals, a leader in gene therapy of somatic stem cells, announced today the company’s clinical program to treat Adrenoleukodystrophy . The company is developing a gene therapy product in collaboration with Professor Patrick Aubourg and Doctor Nathalie Cartier of the National Institute of Health and Medical Research .
The Muscular Dystrophy Association is prepared to underwrite a clinical trial for a promising gene therapy that could preserve and strengthen muscle fibers in patients with neuromuscular diseases.
French scientists mixed gene therapy and bone marrow transplants in two boys to seemingly halt a brain disease that can kill by adolescence.
A breakthrough mix of stem cell and gene therapy halted a lethal brain-wasting illness in two young boys, and could prove effective against other genetic disorders, researchers reported Thursday.
An experimental treatment stabilizes two boys with the rare, fatal degenerative disorder known as ALD. Researchers hail the findings, which come on the tail of other gene-therapy successes. In the third gene-therapy success of recent weeks, French researchers have arrested the progression of the rare and fatal degenerative disorder adrenoleukodystrophy, which was at the heart of the popular ...
French scientists mixed gene therapy and bone marrow transplants in two boys to seemingly halt a brain disease that can kill by adolescence. The surprise ingredient: They disabled the HIV virus so it couldn't cause AIDS, and then used it to carry in the healthy new gene.
Scientists have managed to halt a rare and fatal brain disease with an experimental gene therapy technique using a deactivated version of the AIDS virus, a study published on Thursday showed.
Published: Friday, November 6, 2009 at 5:15 a.m. Last Modified: Friday, November 6, 2009 at 5:15 a.m. Not long ago, gene therapy seemed troubled by insurmountable difficulties.
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