Here are Tuesday’s “Trending Tickers,” the stocks you're following based on your Yahoo Finance ticker searches.

Clovis

A breakthrough in the ongoing fight against cancer drove Clovis Oncology (CLVS) as much as 8% higher on Tuesday, after the FDA awarded its drug, rucaparib with “breakthrough” status. Investors are betting that the FDA designation will help get the drug through the pipeline that much faster. Clovis currently does not have any approved drugs in its portfolio, making these developments critical for shareholders as well as the company. Ovarian cancer is the fifth most prominent cause of cancer-related deaths in women worldwide.

Axalta

Meanwhile, the Oracle of Omaha is at it again. Shares of Axalta (AXTA), a maker of paints and coatings, surged more than 6% on Tuesday after the billionaire investor’s Berkshire Hathaway (BRK-A) agreed to take a position in the company. Specifically, Berkshire is buying 20 million shares for $28 a piece from private equity firm The Carlyle Group. The deal is widely viewed on Wall Street as another sign that Warren Buffett is bullish on global growth.

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Greenbrier

Finally, the locomotive trade is chug-chug-chugging along. Shares of Greenbrier (GBX), a maker of railroad cars as well as marine barges, gained almost 3% at the open after the company posted stronger than expected earnings. Investors were also cheered by guidance which Greenbrier goosed slightly to as much as $2.7 billion for the year. For the quarter ended Feb. 28, Greenbrier said its earnings more than tripled from a year ago with the company benefiting from greater scale and efforts to boost efficiency.

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