The star is accused was recently accused of rape, which led to his departure from the Super Bowl champions.
On Sunday morning he said he would not play in the NFL again, and then took shots at other people in football who have been accused of sexual misconduct.
That included Patriots owner Robert Kraft, who was arrested in connection with a prostitution and sexual trafficking sting in a Florida massage parlour. He has not been punished.
"Different strokes different folks clearly," Brown wrote.
Another target was Brown's longtime Steelers teammate Ben Roethlisberger, who was suspended for four games after he was twice accused of sexual assault. "4 games for Big Ben crazy world I'm done with it," Brown tweeted over a screenshot of a news article about the investigation.
Brown was one of the NFL's most prolific receivers for a decade but was traded out of Pittsburgh and released in Oakland after his off-field antics became too much for those teams.
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The Patriots signed him anyway, and just days later a woman filed a civil lawsuit in Florida accusing him of rape. He played in one game, then was released after the team learned he tried to intimidate a second woman who accused him of sexual misconduct.
Asked by CBS before the game what led to Brown's release, Patriots coach Bill Belichick declined to comment.
Agencies contributed to this report.