Which team will get the victory?
The Cardinals are a 7.5-point favorite in the game, according to Tipico Sportsbook.
The Cardinals are -350 on the money line and the Bears are +265.
The over/under for the game is set at 45.5 points.
Pro Football Network: Cardinals 27, Bears 20
Ben Rolfe writes: "The Cardinals are coming off a bye and will hopefully have Kyler Murray back, which should be a big boost. However, teams coming off a bye have been somewhat sloppy this season, and going on the road to Chicago in December is tough for a warm-weather team. Chicago proved on Thanksgiving they’re not a very good team. The Bears have lost twice at home this year by double-digits. They only kept it tight against the Ravens because Baltimore had to turn to Tyler Huntley in an emergency. Unless the Cardinals beat themselves (or Murray is still limited), this should be a comfortable victory."
Sportsnaut: Cardinals 27, Bears 17
Vincent Frank writes: "(The Bears') struggles will likely come out in full droves against an elite-level Cardinals defense which presents major issues from a pass-rush perspective. And while Chicago’s defense should keep this somewhat close, look for another Cardinals win here."
— azcentral sports (@azcsports) November 30, 2021
Draft Kings: Cardinals will cover vs. Bears in Week 13
It writes: "Even with head coach Kliff Kingsbury’s name thrown in the rumor mill to be desired by the University of Oklahoma to be their next coach, this team hopefully used their bye week to get healthy. The Bears look like they need an extra bye week so that their defense can get their legs under them. They don’t have the line to get to Murray or the secondary to deal with the receiver talent of the Cardinals. A touchdown spread is a lot to cover, but a well-rested Arizona team should be able to pull it off."
Top Bet: Cardinals 28, Bears 22
It writes: "Hopefully for the Cardinals, an extra week of rest, thanks to a bye in Week 12, is enough for quarterback Kyler Murray and wide receiver DeAndre Hopkins to be ready for Week 13’s matchup against Chicago Bears. But even if they continue to sit out, it seems that Arizona is capable of beating a struggling Chicago team. The last time the Cardinals were on the field, Colt McCoy led them to a 23-13 win on the road over the Seattle Seahawks in Week 11. McCoy went 35/44 for 328 passing yards and two touchdowns with zero interceptions. Plus, the Cards still have James Conner taking over in the ground attack while Chase Edmonds continues to recover. Conner had 62 rushing yards and a touchdown on 21 carries against Seattle and 37 receiving yards on five catches. Arizona’s main backups on offense play more cohesive football than the starters of the Detroit Lions who gave Chicago trouble in Week 12."
Sportsnaut: Cardinals 31, Bears 20
Matt Johnson writes: "Both Kyler Murray and DeAndre Hopkins are trending towards a Week 13 return. But even if they don’t play, we’ve seen Colt McCoy beat better teams than Chicago. It’s likely a close loss to McCoy and a blowout defeat if Murray starts."
FiveThirtyEight.com: Cardinals have a 75% win probability
The site fives the Bears a 25% win probability in the NFL Week 13 game.
ESPN: Cardinals have a 76.4% chance to win
The site's Football Power Index gives the Bears a 23.5% chance to pick up the victory in the Week 13 NFL game.
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This article originally appeared on Arizona Republic: Arizona Cardinals vs. Chicago Bears picks, odds NFL Week 13 game