Buffalo Bills vs. New England Patriots picks, predictions: Who wins NFL Week 13 game?

The Buffalo Bills and New England Patriots play on Thursday Night Football in a game on the NFL Week 13 schedule.

Which team will win the game?

Check out these NFL Week 13 picks and predictions for the game, which can be seen at 6:15 p.m. MST on Amazon Prime Video.

The Bills are a 3.5-point favorite in the game.

NFL Week 13 picks: Bills vs. Patriots | Steelers vs. Falcons | Broncos vs. Ravens | Packers vs. Bears | Jaguars vs. Lions | Browns vs. Texans | Jets vs. Vikings | Commanders vs. Giants | Titans vs. Eagles | Seahawks vs. Rams | Dolphins vs. 49ers | Chiefs vs. Bengals | Chargers vs. Raiders | Colts vs. Cowboys | Saints vs. Buccaneers

The Arizona Republic: Bills 27, Patriots 20

Jeremy Cluff writes: "The Patriots really need to win this game to help their chances at making the playoffs. We just don't see that happening. The Bills will be too much."

Bookies.com:  Take the Patriots with the points vs. Bills

Bill Speros writes: "The Patriots need this win to have any hope of a playoff spot. The last time they beat the Bills, the Patriots ran the ball on 46 of 49 offensive snaps. Whatever works."

NFL Week 13 odds: Bills vs. Patriots | Steelers vs. Falcons | Broncos vs. Ravens | Packers vs. Bears | Jaguars vs. Lions | Browns vs. Texans | Jets vs. Vikings | Commanders vs. Giants | Titans vs. Eagles | Seahawks vs. Rams | Dolphins vs. 49ers | Chiefs vs. Bengals | Chargers vs. Raiders | Colts vs. Cowboys | Saints vs. Buccaneers

ESPN: Bills have a 73.7% chance to win the Week 13 game

The site gives the Patriots a 26.1% chance to get the victory.

Draft Kings: Go with the Patriots with the points vs. Bills

It writes: "This is a rare TNF game that isn’t a short-week contest since both teams played last week on Thanksgiving. Buffalo has strung together wins the past month, but they haven’t been pretty. They beat the Browns pretty handily, but last week was a struggle to beat Detroit and they lost to the Vikings and Jets prior to that. I think Bill Belichick’s squad keeps this close enough. Buffalo wins but New England covers."

How to watch:NFL Week 13 schedule, television information

Sports Betting Dime: Bills 19.6, Patriots 11.7

The site's formula predicts that the Bills will win the Week 13 NFL game.

OddsChecker: Bills won't cover vs. Patriots

It writes: "Given the recent history and the Pats defense getting exposed last week it’s clear that Buffalo deserves to be the favorites here. However, their struggling defense and weak performances against the AFC East say this is going to be closer than many think."

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NFL playoff picture Week 13:NFC East a beast with four teams in postseason position

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Buffalo Bills vs. New England Patriots predictions for NFL Week 13