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  • Meet the new contestants for season five of 'The Masked Singer'

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  • Israel sentences Palestinian lawmaker to two years in prison

    An Israeli military court has sentenced a prominent Palestinian lawmaker to two years in prison in a plea bargain that convicted her of belonging to an outlawed group. Khalida Jarrar, a member of the Popular Front for the Liberation of Palestine, has been held without charge since October 2019. Israel, along with the U.S. and other Western allies, considers the PFLP a terror group.

  • Shots fired as Myanmar journalist live-streams police raid to detain him

    The DVB news agency confirmed the detention of Kaung Myat Hlaing in a statement and called for his release, as well as the release of other detained journalists. An officer who answered the telephone at the Myeik Township Police Station said news of the reporter's detention had not been confirmed and hung up.

  • Beijing dismisses alleged Chinese hacking of Indian vaccine makers

    China on Tuesday rejected an allegation by a cyber intelligence firm that a state-backed hacking group targeted the IT systems of two Indian coronavirus vaccine makers. Cyfirma told Reuters that hacking group APT10, known as Stone Panda, had identified gaps and vulnerabilities in the IT infrastructure and supply chain software of Bharat Biotech and the Serum Institute of India (SII), the world's largest vaccine maker. "Without showing any evidence, the relevant party made baseless speculation, distorted and concocted facts, to malign a specific party," China's foreign ministry told Reuters.

  • Rep. Adam Kinzinger tore into Sen. Josh Hawley for his 'smug' CPAC speech, saying 5 people died because of 'what you did'

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  • UK royal Meghan awarded $630,000 in costs after court privacy win

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  • Covid-19: Sri Lanka chooses remote island for burials

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  • An eagle-eyed 'Harry Potter' fan noticed leads being replaced by random actors in a 'Prisoner of Azkaban' scene

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  • What's in a name for a vaccine campaign? Maybe the end of the pandemic

    An unidentified doctor talks with a boy who holds a lollipop reward after participating in a measles vaccine research program in Upper Darby, Pennsylvania, in 1963. NASA/PhotoQuest/Getty ImagesNearly 50 million people in the U.S. had received at least one dose of the coronavirus vaccine by March 1, and millions of others have spent hours online trying to get an appointment. But soon, the demand could fall because of vaccine hesitancy. How is the government going to get people on board? From my research, I have found that an important part of a successful vaccine campaign is in the name. As a health communication scholar who studies the history of epidemics, I have been interested in the naming and public delivery of the COVID-19 government response. In many ways, this moment parallels crises of the past, as people in previous epidemics and pandemics also struggled to find ways to protect themselves against deadly disease. Dr. Anthony Fauci, the head of the National Institute of Allergy and Infectious Diseases, speaking about Zika in January 2016. Win McNamee/Getty Images Abandoning the ‘Operation Warp Speed’ name In the week leading up to the 2021 presidential inauguration, the Biden transition team announced that the White House’s national COVID-19 vaccine plan would no longer be called “Operation Warp Speed,” the name coined by Biden’s predecessor, Donald Trump. On Jan. 21, 2021, the Biden administration released its 200-page COVID-19 plan, “The National Strategy for the COVID-19 Response and Pandemic Preparedness.” The change in names not only broadened the focus to include additional safety measures to curb transmission during the distribution process. It also signified a profound shift in the administration’s approach and consideration of the pandemic itself. Dr. Anthony Fauci and other public health experts criticized the “Operation Warp Speed” name, arguing that it falsely conveyed a lack of scientific rigor and adherence to safety protocol in the vaccine approval process. In a May 15, 2020, press conference, Trump explained the campaign name, stating, “It’s called ‘Operation Warp Speed.’ That means big, and it means fast. A massive scientific, industrial and logistical endeavor unlike anything our country has seen since the Manhattan Project.” Fauci and others believed that the name “Operation Warp Speed” could have undermined public trust in any COVID-19 vaccine to be developed, feeding into theories and misconceptions of the anti-vaccine movement. It also marked a historical deviation in the identification of vaccine campaigns for the general public. The names we Americans use broadly today, inoculation and vaccination, emerged as the names for very specific immunization procedures against a specific disease, smallpox. Smallpox: A big controversy In the past, immunization terms stemmed from the induced immunological protection against smallpox. During the Boston smallpox epidemic of 1721, for example, Puritan minister Cotton Mather and Colonial physician Dr. Zabdiel Boylston introduced the practice of inoculation in hopes of protecting the town. Onesimus, an enslaved man who was in bondage to Mather, had told Mather of the practice and how he had been inoculated as a child in Africa. The practice involved intentionally infecting people with smallpox in hopes of reducing its severity. People fiercely discussed this controversial approach in public discourse, even spurring James Franklin, older brother of Benjamin, to create the New England Courant as an outlet to oppose its practice. Many articles in The Courant, Boston Gazette and the Boston News-Letter, along with pamphlets, argued for and against the practice of inoculation. This cemented the term in 18th-century vocabulary, along with its alternative name, “variolation.” This practice, and growing public familiarity with it, set the stage for acceptance of the first vaccine, which would change the course of disease. In 1798, English physician Dr. Edward Jenner proposed that inducing a mild cowpox infection could protect against smallpox – which he called a “vaccine,” from vaccinia, meaning cowpox. Millions of people already have been vaccinated. Michael Ciaglo/Getty Images Say its name Immunization campaigns for approved and established vaccines have often gone unnamed, simply listing the disease name, location and date, like the 1916 typhoid vaccine campaign in North Carolina’s Catawba County, northwest of Charlotte, North Carolina. Even sponsored vaccine programs have not necessarily taken on the name of the supporting corporation. In 1926, the Metropolitan Life Insurance Co. donated US$15,000 toward the eradication of diphtheria in New York. Despite this contribution, the campaign went unnamed. In the trial and development stage, vaccines were not typically named, even in the press. News articles referred to the “anti-disease” vaccine – that is, “anti-smallpox,” “anti-typhoid,” “anti-tetanus” – sometimes including the lead scientist’s last name, as with the Enders measles vaccine. For example, although polio vaccine trials in 1954 labeled the recruited child participants “polio pioneers,” the vaccine itself was called the “anti-polio” or Salk vaccine. Nicknaming vaccines can be a problem When vaccine campaigns have been named, catchy or abstract names can be problematic, especially in the experimental stages. The 1950s gamma globulin trials prompted confusion with the nickname “Operation Lollipop,” which referred to the “all-day sucker” given to children after the injection. Some people misunderstood, believing that scientists had delivered the actual polio virus in the candy to participants, prompting clarification that the name “had nothing to do with the experiment itself.” A Star Wars poster from 1977 encouraged immunization. Centers for Disease Control and Prevention More often, campaigns and slogans have been used in catch-up immunization drives after already widely distributed vaccines, as in the polio vaccine “Wellbee,” Utah’s 1967 “Muzzle Measles,” the 1977 Star Wars “Parents of Earth” message or the 1997 Dr. Seuss Immunization Awareness Campaign. These programs highlighted the importance of existing vaccines, rather than introducing new ones. As public health officials have noted, the title “Operation Warp Speed,” combined with the lack of a strategic COVID-19 response plan under the Trump administration, took away from the strict adherence to safety protocols that vaccine producers and the Food and Drug Administration have followed. In a Gallup Panel survey from Dec. 15, 2020, to Jan. 3, 2021, 65% of participants said they would get the vaccine, with divisions in age, race, education and party affiliation. The name “Operation Warp Speed” paired with coronavirus misinformation, much of it directly from Trump, likely contributed to the lack of trust in the vaccines before they were even developed. At least 75% to 80% of the population needs to become immunized – the number needed for herd immunity – to end of the pandemic, according to Fauci. Thus, I believe it will be important to develop a trustworthy campaign and a name that bolsters confidence. The Biden administration is not starting from scratch. I believe that the Biden administration’s adoption of a new direct name for its response plan is the first step toward pandemic recovery. Building confidence across various groups and communities will be critical for herd immunity to be achieved. The new campaign name, then, initiated what needs to be a straightforward, factual approach, integral to widespread COVID-19 immunization.This article is republished from The Conversation, a nonprofit news site dedicated to sharing ideas from academic experts. It was written by: Katherine A. Foss, Middle Tennessee State University. Read more:How does the Johnson & Johnson vaccine compare to other coronavirus vaccines? 4 questions answeredCan vaccinated people still spread the coronavirus? Katherine A. Foss does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their academic appointment.

  • Soleil Moon Frye 'lost sight' of herself. Facing her darkest memories brought her back

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  • There Are 6 Treatments Helping Patients Survive COVID-19

    Carl Court/GettyBy William G. Bain, Georgios D. Kitsios, and Tomeka L. SuberA year ago, when U.S. health authorities issued their first warning that COVID-19 would cause severe “disruption to everyday life,” doctors had no effective treatments to offer beyond supportive care.There is still no cure, but thanks to an unprecedented global research effort, several treatments are helping patients survive COVID-19 and stay out of the hospital altogether.COVID-19 treatments target two broad problems: the coronavirus’s ability to spread through the body, and the damage caused by the body’s immune system response. When the virus enters the body, it takes over cells and uses them to replicate itself. In response, the body sends inflammatory signals and immune cells to fight the virus. In some patients, that inflammatory response can continue even after the virus is under control, leading to damage in the lungs and other organs.The best tool is prevention, including using face masks and vaccines. Vaccines train the immune system to fight off attackers. With less risk of an uncontrolled infection, they can cut the risk of death from COVID-19 to near zero. But vaccine supplies are limited, even with a third vaccine now authorized for U.S. use, so treatments for infected patients remain crucial.This Drug Is a Staple of COVID Treatment. Should It Be?As doctors who work with COVID-19 patients, we have been following the drug trials and success stories. Here are six treatments commonly used today for COVID-19. As you’ll see, timing matters.Keeping you out of the hospitalTwo promising types of treatments involve injecting antiviral antibodies into high-risk COVID-19 patients before the person becomes severely ill.Our bodies naturally create antibodies to recognize foreign invaders and help fight them off. But natural antibody production takes several days, and SARS-CoV-2—the coronavirus that causes COVID-19—replicates fast. Studies show that injecting patients with antibodies soon after symptoms begin can help protect patients against serious infection.Monoclonal antibodies: These lab-engineered antibodies can bind to SARS-CoV-2 and prevent the virus from entering cells and infecting them. They include Bamlanivimab and the combined therapy casirivimab/imdevimab developed by Regeneron. The U.S. Food and Drug Administration granted emergency use authorization for these therapies because they have been found to protect high-risk patients from hospitalization and death. Once patients are sick enough to need hospitalization, however, studies haven’t found a proven benefit from them.Convalescent plasma: Another way to deliver antibodies involves blood drawn from patients who have recovered from COVID-19. Convalescent plasma is primarily given in research settings because the clinical evidence so far is mixed. Some trials show benefits early in the disease. Other studies have not shown any benefit in hospitalized patients.There may be a role for convalescent plasma as a supplemental therapy for some patients because of the growing threat of mutated SARS-CoV-2 variants, which may evade monoclonal antibody therapy. However, careful research is necessary.If you are hospitalizedOnce patients become so sick that they have to be hospitalized, treatments change.Most hospitalized patients have difficulty breathing and low oxygen levels. Low oxygen occurs when the virus and corresponding immune response injure the lungs, resulting in swelling in lung air sacs that restricts the amount of oxygen getting into the blood. Patients hospitalized with COVID-19 usually need supplemental medical oxygen to help them breathe. Doctors frequently treat patients on oxygen with the antiviral agent remdesivir and anti-inflammatory corticosteroids.Remdesivir: Remdesivir, originally designed to treat hepatitis C, stops the coronavirus from replicating itself by interfering with its genetic building blocks. It has been shown to shorten the length of hospital stays, and doctors may prescribe it to patients on oxygen shortly after arrival in the hospital.Chris Christie Says He’s Out of the Hospital After Week-Long Stay for COVID-19Corticosteroids: Steroids calm the body’s immune response and have been used for decades to treat inflammatory disorders. They are also widely available, cheap and well-studied medications, so they were among the first therapies to enter clinical trials for COVID-19. Several studies have shown that low-dose steroids reduce deaths in hospitalized patients who are on oxygen, including the sickest patients in the intensive care unit, or ICU. Following the findings of the landmark RECOVERY and REMAP-CAP COVID-19 studies, steroids are now the standard of care for patients hospitalized with COVID-19 who are treated with oxygen.Blood thinners: Inflammation during COVID-19 and other viral infections can also increase the risk of blood clots, which can cause heart attacks, strokes and dangerous clots in the lungs. Many patients with COVID-19 are given the blood thinners heparin or enoxaparin to prevent clots before they occur. Early data from a large trial of COVID-19 patients suggests that hospitalized patients benefit from higher doses of blood thinners.Some patients with COVID-19 become so sick that they need an ICU for high levels of oxygen support or a ventilator to help them breathe. There are several therapies available for ICU patients, but ICU patients have not been found to benefit from high doses of blood thinners.Treating the sickest patientsICU patients with COVID-19 are more likely to survive if they receive steroids, studies have found. However, low-dose steroids alone may not be enough to curb excessive inflammation.Tocilizumab: Tocilizumab is a lab-generated antibody that blocks the interleukin-6 pathway, which can cause inflammation during COVID-19 and other diseases. New results from the REMAP-CAP trial that have not yet been peer-reviewed suggest that a single dose of tocilizumab given within one to two days after being placed on respiratory support reduced the risk of death in patients already receiving low-dose steroids. Tocilizumab has also been shown to benefit patients with high levels of inflammation in early results from another trial.These innovative therapies can help, but careful supportive care in the ICU is also crucial. Decades of extensive research have defined core management principles for helping patients with severe lung infections who need ventilators. These include avoiding underinflation and overinflation of the lung by the ventilator, treating pain and anxiety with low levels of sedative medications, and periodically placing certain patients with low oxygen levels on their belly, among many other interventions. The same key principles likely apply to patients with COVID-19 to help them survive and recover from a critical illness that can last weeks or months.Medical progress since the start of the pandemic has been awe-inspiring. Doctors now have vaccines, antiviral antibodies for high-risk outpatients and several treatments for hospitalized patients. Continued research will be crucial to improve our ability to fight a disease that has already claimed more than 2.5 million lives worldwide.William G. Bain, Georgios D. Kitsios, and Tomeka L. Suber are assistant professors of medicine at the University of PittsburghRead more at The Daily Beast.Get our top stories in your inbox every day. Sign up now!Daily Beast Membership: Beast Inside goes deeper on the stories that matter to you. Learn more.

  • U.S. blacklists two leaders of Yemen's Houthi movement

    The United States on Tuesday imposed sanctions on two military leaders of the Houthi movement in Yemen, accusing them of procuring weapons from Iran and organizing attacks, in the Biden administration's first punitive action against the group. The sanctions contrast with the State Department's decision last month to revoke terrorist designations on the group imposed by President Donald Trump's administration on its last full day in office, over concern that they would exacerbate Yemen's humanitarian crisis.

  • Israel moving to protect hundreds of personnel against ICC probe

    Israel estimates that hundreds of its citizens might be subject to war crimes probes by the International Criminal Court, whose jurisdiction it rejects, and is working on how to protect them, the Defence Minister said on Tuesday. Including himself among Israelis who could be threatened with arrest, Benny Gantz told Reuters: "I was never afraid to go across enemy lines, I will continue to stand wherever I have to." The Hague-based tribunal ruled last month that it has jurisdiction over the occupied West Bank, Gaza and East Jerusalem.

  • U.S., EU impose sanctions on Russia for Navalny poisoning, jailing

    The United States on Tuesday imposed sanctions to punish Russia for what it described as Moscow's attempt to poison opposition leader Alexei Navalny with a nerve agent last year, in President Joe Biden's most direct challenge yet to the Kremlin. The sanctions against seven senior Russian officials, among them the head of its FSB security service, and on 14 entities marked a sharp departure from former President Donald Trump's reluctance to confront Russian President Vladimir Putin.

  • Eddie Murphy and Arsenio Hall said they were 'forced' to cast a white actor in 'Coming to America'

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    President Joe Biden's pick to head the Office of Management and Budget, Neera Tanden, has withdrawn her nomination after she faced opposition from key Democratic and Republican senators for her controversial tweets. Thirteen of the 23 Cabinet nominees requiring Senate approval have been confirmed, most with strong bipartisan support. “Unfortunately, it now seems clear that there is no path forward to gain confirmation, and I do not want continued consideration of my nomination to be a distraction from your other priorities,” Tanden wrote in a letter to Biden.

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  • Philippine president fires ambassador seen assaulting staff

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