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Colts vs Jaguars betting odds, TV, injuries in NFL Week 2

The Indianapolis Colts go for their first victory of the season when they visit the Jacksonville Jaguars in Week 2 action.

The Colts are coming off a Week 1 20-20 tie with the Houston Texans. Indianapolis trailed by 17 points early in the fourth quarter before rallying to send the game to overtime. Rodrigo Blankenship missed a winning field goal in overtime, leading to his release. Matt Ryan, Jonathan Taylor and Michael Pittman Jr. – who is out for Week 2 – piled up big numbers.

The Jaguars fell 28-22 to the Washington Commanders in Week 1 after scoring 19 straight points in the second half and leading by 8 early in the fourth quarter. Trevor Lawrence quickly developed a favorite target in Christian Kirk, and linebacker Devin Lloyd led Jacksonville in tackles.

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Here's what you should know about the Week 2 matchup.

Colts can't win in Jacksonville

Remember how the Colts were battling a Week 1 curse last week and sort of broke it? Well, here comes another one.

The Colts haven't won in Jacksonville since 2014, losing seven straight to the Jaguars as the road team. And the circumstances of some of these defeats are disheartening.

Year / Final score

2021 / 26-11*

2020 / 27-20**

2019 / 38-20

2018 / 6-0***

2017 / 30-10

2016 / 30-27****

2015 / 51-16

*-In the 2021 season finale, the Colts needed a win to clinch an AFC playoff berth, and the Jaguars were in line to get the No. 1 NFL Draft pick. The Colts were never in the game and missed the playoffs. Jacksonville finished with a 3-14 record and still got the No. 1 pick. It picked edge rusher Travon Walker out of Georgia. He had 4 tackles, including a sack, in Week 1.

**-The Jaguars took advantage of Colts mistakes in the 2020 season opener. It turned out to be Jacksonville's only win that season.

***-The Jaguars stopped a seven-game losing streak while snapping the Colts' five-game winning streak.

****-The game was played in London.

When do the Colts play in Week 2?

The game is at 1 p.m. ET on Sunday, Sept. 18, 2022, at TIAA Bank Field.

How can I watch, stream the Colts-Jaguars game?

The game will be on CBS, with Tom McCarthy on play-by-play and Tiki Barber with analysis. It can also be seen on colts.com and the NFL+ app.

How can I listen to the Colts play?

The game will be carried on 93.5, 97.1 and 107.5 FM in Indianapolis, with Matt Taylor on play-by-play, Rick Venturi with analysis and Larra Overton with sideline reporting. The game can also be heard on SiriusXM Channels 383 and 813.

Are the Colts favored against the Jaguars?

The Colts are 3-point favorites, according to Draft Kings. The over/under is 45 total points.

What is the Colts forecast?

Cloudy skies, scattered storms and temperatures in the 80s are forecast for Jacksonville.

Colts injury report

Colts who are out for Sunday: WR Alec Pierce (concussion), WR Michael Pittman Jr. (quad), LB Shaquille Leonard (back); questionable: DL DeForest Buckner (hip), CB Kenny Moore II (hip).

Jaguars injury report

The Jaguars report no injuries.

Who is the Colts kicker?

Chase McLaughlin, who kicked for the Colts in 2019, beat out Luke Havrisik to replace the released Rodrigo Blankenship.

Colts players to watch

Here's where Colts rank in NFL yardage: Matt Ryan (352 passing, 2nd); Jonathan Taylor (161 rushing, 2nd); Michael Pittman Jr. (121 receiving, tied for 7th). ... The Colts' 517 yards gained rank 1st in the NFL. ... Zaire Franklin had 8 tackles in Week 1. ... Kwity Paye had 2 sacks.

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Jaguars players to watch

Trevor Lawrence, starting his second season, completed 24-of-42 passes for 275 yards, 1 touchdown and 1 interception. ... Christian Kirk had 6 catches for 117 yards. ... James Robinson carried 11 times for 66 yards. ... Devin Lloyd had 11 tackles.

Colts tickets

See what's available in Jacksonville

This article originally appeared on Indianapolis Star: Colts vs Jaguars betting odds, TV, injuries, tickets in NFL Week 2