Colts vs Titans: Final injury report as AFC South leaders meet in NFL Week 7

We're not to the mid point of the NFL season, but this matchup between the Indianapolis Colts and Tennessee Titans carries unusual importance.

Indianapolis is almost out of opportunities to gain an edge on AFC South opponents. Though the Colts (3-2-1) would be in the playoffs if the season ended before Sunday, they're just 1-2-1 against division opponents.

According to the New York Times, if the Colts win Sunday, they have a 73% chance of making the AFC playoffs. If they lose, those chances drop to 47%.

Tennessee (3-2), which beat the Colts 24-17 in Week 4, would have a 69% chance of making the playoffs with a win, 44% with a loss. A win would also give the Titans a tiebreaker edge over the Colts. They have won three straight and are coming off their bye week.

The Titans ran to an early 21-point lead in Week 4 and held off two Indianapolis threats in the fourth quarter (fumble recovery, missed field goal).

Tennessee won last year's game in Nashville, but the Colts won the previous three there.

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When do the Colts play the Titans?

The game is at 1 p.m. ET Sunday, Oct. 23, 2022, at Nissan Stadium in Nashville.

How can I watch the Colts vs. the Titans?

The game will be on CBS, with Andrew Catalon on play-by-play, James Lofton with analysis and Don Bell with sideline reporting. The game is also available on the NFL+ app.

How can I listen to the Colts-Titans game?

The game can be heard on 93.5, 97.1 and 107.5 FM in Indianapolis, with Matt Taylor on play-by-play, Rick Venturi with analysis and Larra Overton with sideline reporting. The game can also be heard on SiriusXM Channels 388 and 813.

Colts vs. Titans betting odds

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The Titans are 2.5-point favorites, according to Draft Kings. The over/under is 42 points.

The Colts are 3-3 against the spread, covering the past two weeks. The Colts game went over last weekend for the first time this season. The Colts are 2-0 overall as an underdog.

Titans are 3-2 against the spread, covering in the three recent wins. Two Tennessee games have gone over, and three under. All their games have finished within 5 points of the over/under. The Titans are 1-1 overall as the favorite.

Colts-Titans weather forecast

Partly Cloudy skies and a high in the upper 70s are forecast for Sunday in Nashville.

Colts injury report

Colts who have been ruled out: DE Kwity Paye (ankle), LB JoJo Domann, WR Keke Coutee (concussion), LB Shaquille Leonard (concussion/nose/back); others on the injury list but are full participants in practice: TE Kylen Granson (neck), RB Jonathan Taylor (ankle), S Julian Blackmon (ankle), RB Nyheim Hines (concussion), RB Deon Jackson (quad).

Titans injury report

Titans who have been ruled out: LB Zach Cunningham (elbow), FB Tory Carter (neck), LB Joe Jones (knee), G Nate Davis (foot); questionable: WR Kyle Philips (hamstring); full participants in participants: LB Bud Dupree (hip), S Armani Hooker (concussion).

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The Colts have vaulted out of last place in points per game (17.2, 27th) with their performance against Jacksonville. ... With last week's 58-pass game plan, they are the 3rd-most pass-happy team in the NFL (65.7% of their plays). ... Matt Ryan has completed 67.2% of his passes for 1,765 yards, 8 touchdowns and 7 interceptions. He has been sacked 21 times, but 0 last week. ... Michael Pittman Jr. has 38 catches for 417 yards. ... Their 83.7 rushing yards per game are 29th. ... Jonathan Taylor has missed the past two games and leads them with 328 rushing yards. Deon Jackson has 101 rushing yards and 14 catches for 108 yards. ... The Colts score touchdowns on 47.4% of their red zone trips (25th). ... Indianapolis gains 350 yards per game (14th). ... The Colts' stout rushing defense suffered a hit last week, and they now rank 21st (121 yards allowed per game). ... Zaire Franklin has 65 tackles. ... DeForest Buckner and Kwity Paye have 3 sacks.

Titans mix run, pass

Tennessee scores a touchdown on 92.3% of its red zone drives (No. 1 in the NFL). ... However, the Titans' 278 yards per game are 31st. ... Tennessee has an almost even 50-50 split in rushing/passing offensive plays. ... Derrick Henry has 408 rushing yards (3.9 per carry) and 5 touchdowns. ... Ryan Tannehill completes 65.1% of his passes for 965 yards, 6 TDs and 3 interceptions. He has been sacked 12 times. ... Robert Woods has 17 catches for 204 yards. ... RB Dontrell Hilliard has 3 receiving TDs. ... Titans stop opponents on 27.1% of their 3rd-down plays (No. 2). ... Tennessee opponents rush for 103.2 yards per game (5th-fewest allowed). ... Kevin Byard and David Long have 37 tackles. ... Denico Autry has 4 sacks.

This article originally appeared on Indianapolis Star: Colts vs. Titans injuries, odds, TV, weather in NFL Week 7 game