A fifth-round pick out of Virginia Tech, Mitchell has been inactive for the Lions' first three games. He caught 52 passes for 838 yards in three college seasons, but the Lions brought him along slowly in training camp as he returned from 2021 knee injury.
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Mitchell will dress as the Lions' third tight end after the team waived Shane Zylstra on Saturday, one of two moves it made to clear roster spots for kicker Dominik Eberle and offensive lineman Dan Skipper.
Eberle will handle kicking duties today in place of the injured Austin Seibert, and Skipper is expected to make his third straight start at left guard in place of the injured Jonah Jackson.
Along with Skipper and Jackson, the Lions (1-2) ruled running back D'Andre Swift and receivers Amon-Ra St. Brown and DJ Chark out for today's game with injuries. John Cominsky (wrist) and rookie defensive tackle Demetrius Taylor also are inactive for the Lions.
This article originally appeared on Detroit Free Press: Detroit Lions rookie TE James Mitchell to make NFL debut vs. Sehawks