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"I would say to my Republican friends, and I do have some, 'Take back your party.' The Republican party, the Grand Old Party, has made tremendous contributions to our country, founded by Lincoln, but over the years tremendous contributions to our country. Don't let your party be hijacked by a cult - essentially that is what is happening, and it isn't good for the country," she said during a question and answer session.
"They're off the spectrum. This is not conservative, which is of course more than a legitimate position to hold. This is radical, right-wing, off the spectrum, anti-governance. And if you're anti-governance, it's very hard to govern."
Pelosi is visiting England for a meeting of parliamentary leaders from G7 countries.