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As the founder and former chief executive officer of the disgraced blood-testing start-up that wowed the tech investment world before collapsing in a storm over the efficacy of the technology supposedly at its core, Ms Holmes faces up to 20 years in prison if convicted.
Theranos was at one point valued at approximately $9bn, but is now a byword for corporate misconduct, with Ms Holmes accused of lying to patients about testing, and investors about projected revenues.
The trial got underway in federal court in San Jose, California on Tuesday after a string of delays due to the coronavirus pandemic, and the defendant’s surprise pregnancy.
Anticipated to last approximately three months, the final chapter in the spectacular rise and fall of Ms Holmes is expected to see defence lawyers get creative when faced with a strong case from the prosecution. It is the most-anticipated trial of the year.