What would endemic stage COVID look like? US nearly done with 'pandemic phase' of virus

The COVID-19 pandemic isn't over. But Ohioans may be able to look forward to the virus entering a new transitional phase.

After more than two years of COVID causing tens of millions of cases and hundreds of thousands of deaths, the nation is almost finished with the "pandemic phase," of the virus, said Dr. Anthony Fauci, chief medical adviser for President Joe Biden.

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Fauci, head of the National Institute of Allergy and Infectious Diseases, made the comment Tuesday on "PBS NewsHour."

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"We are certainly right now in this country out of the pandemic phase," Fauci told PBS' Judy Woodruff. "Namely, we don't have 900,000 new infections a day, and tens and tens and tens of thousands of hospitalizations, and thousands of deaths. We are at a low level right now."

Despite Fauci's comments, cases are rising again in Ohio and other parts of the country.

Ohio reported 8,731 new cases of the virus April 21, which is an increase from the 3,828 three weeks earlier. That's still far lower than the 32,487 reported at the height of the winter surge Jan. 3, data shows.

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The pandemic was declared by the World Health Organization on March 11, 2020 and the pandemic has not ended, according to the organization's designation. A pandemic is a global outbreak of a serious new illness that requires “sustained transmission throughout the world," Fauci told USA TODAY in February 2020.

Although the pandemic continues, here's what a transition to the endemic phase of COVID might look like in the coming weeks and months.

What does endemic mean?

The Centers for Disease Control and Prevention defines endemic as the “constant presence and/or usual prevalence” of a disease within a population in a certain geographic area.

An endemic disease spreads at a baseline level every year without causing major disruption to people's lives, said Dr. Donald Burke, professor of epidemiology at the University of Pittsburgh Graduate School of Public Health.

“Things that are endemic are present for long periods of time without interruption, continuously circulating in the population," like the common cold, he said.

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A disease can be endemic in one country but can be considered an outbreak or an epidemic in another country, explained Dr. Pritish Tosh, an infectious diseases physician and researcher at the Mayo Clinic.

For example, malaria is considered endemic in some parts of the world where mosquitos carry the parasite. However, a high number of malaria cases in the United States would be considered an epidemic if it were not contained.

What’s the difference between an epidemic and an endemic?

An epidemic is a sudden increase of a disease above what is normally expected among the population in a certain area, according to the CDC.

Epidemics aren't just caused by diseases that result from viruses or bacteria, the agency says. For example, diabetes and obesity exist in large enough proportions in the U.S. to be considered epidemics. Similarly, a sudden increase in addiction to opioids over the past several years is accurately called an “opioid epidemic.”

The part of the word “epi” means "to be upon," Burke said, and “demic” comes from “demos,” which means "people."

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“Epidemic means something that comes out and is among the people,” he said. “Things that are epidemic are things that are unusual that are not there and then appear.”

Endemic means "something that's within the people," he added. Many epidemics have turned into endemics.

But an endemic disease does not necessarily mean that it will exist forever. Some endemic diseases have been eliminated in the U.S. after achieving herd immunity through vaccines and natural infection.

What are some endemic diseases?

The four common cold coronaviruses, which are considered cousins of SARS-CoV-2, the virus that causes COVID-19, are considered endemic in most parts of the world, including the U.S., Burke said.

“We don’t notice them,” he said. “They’re transmitted, they’re constant.”

Many childhood diseases also are endemic, he said. The measles, for example, used to be endemic in the U.S.

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“In the old days … they were commonplace. Everybody got them,” Burke said. But childhood vaccines helped impede transmission, almost eliminating the measles from the U.S.

However, the measles is still considered endemic in some parts of the world, Tosh said. If the highly infectious virus was brought in from another country, it could cause an outbreak and possibly lead to an epidemic in the U.S.

For example, a series of outbreaks in 2019 led to more than 1,200 measles cases in the U.S. – the highest number of cases recorded in the country since 1992, according to the CDC. The agency attributed the outbreaks to travelers who got measles abroad and pockets of unvaccinated people.

Could COVID-19 become endemic?

It’s likely SARS-CoV-2 is here to stay, health experts say.

“It appears as though this virus is likely to remain endemic in populations at least for several years, possibly indefinitely,” Tosh said.

A January study found that the virus “could join the ranks of mild, cold-causing … human coronaviruses in the long run,” according to Emory University and Penn State University scientists.

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The model, published in the peer-reviewed journal Science, compares SARS-CoV-2 to four common cold coronaviruses plus the SARS and MERS viruses, which surfaced in 2003 and 2012, respectively.

Researchers determined from the model that if the novel coronavirus continues to circulate in the general population and most people are exposed to it from childhood, it could be added to the list of common colds.

USA Today reporters Adrianna Rodriguez and Ryan W. Miller and Dispatch reporter Max Filby contributed to this story.

This article originally appeared on The Columbus Dispatch: What would endemic COVID-19 look like? US exiting 'pandemic phase'