Since the film was released on 16 December, it has become a huge hit, making $1.731bn (£1.424bn) after just three weeks of release.
This positions it as the seventh highest-grossing film of all time.
When asked how it feels to have three films in the top 10 charts ranking the biggest movies of all time, the Titanic director told Variety he “doesn’t look at it in those terms”.
Cameron said he is just happy that people want to be back in cinemas, stating: “Enough of the streaming already. I’m tired of sitting on my a**.”
He added: “As as society, we need to go to the cinema.”
Considering the film’s box office figures, Cameron, who has already shot the third Avatar film, will now proceed with a fourth and fifth instalment.
Also featured in the top 10 films of all time are Avengers: Infinity War and Avengers: Endgame, released in 2019 and 2020, respectively, and 2015 film Star Wars: The Force Awakens.
All of these totals are unadjusted for inflation. With inflation taken into account, the biggest film of all time remains 1939’s Gone with the Wind.