(Reuters) - Collegium Pharmaceutical Inc said the U.S. Food and Drug Administration said it would not be able to complete its review of the company's opioid painkiller by Monday. The company's shares fell 8 percent in extended trading. Collegium did not say if the FDA had given any reason for not being able to complete the review by the set date of Oct. 12 or when it expected the review would now be completed. Collegium's long-acting experimental oral opioid painkiller, Xtampza, is meant to be taken after a meal for maximum effect. A panel of outside advisers to the FDA had unanimously voted in favor of the drug on Sept. 11. But, two days before that FDA staff had said that if the drug was taken without food, it could give insufficient relief, which could lead to overdosing. The abuse of opioids – a class of drugs that include heroin and prescription painkillers – has long been a concern. An overdose of such drugs can produce euphoric highs and even disrupt parts of the brain that control breathing. The FDA's ruling on Xtampza will be keenly watched by other developers of abuse-deterrent versions of painkillers. These include Pernix Therapeutics Holdings Inc, Egalet Corp, KemPharm Inc, Pain Therapeutics Inc and Acura Pharmaceuticals Inc. Collegium's shares were trading at $18.25 after the bell. They closed at $20.09 on the Nasdaq. (Reporting by Rosmi Shaji in Bengaluru; Editing by Savio D'Souza)
Our goal is to create a safe and engaging place for users to connect over interests and passions. In order to improve our community experience, we are temporarily suspending article commenting
- Yahoo News
President Biden was caught on a hot mic Monday appearing to call Fox News reporter Peter Doocy a "stupid son of a bitch" in response to a question asked at the start of a White House event on lowering the prices of consumer goods.
Did the Bucs just lose their quarterback, too?
- Bills Wire
What Sean McDermott said about #Bills' kickoff with 13 seconds left vs. #Chiefs:
Prince William Cheers on Prince George at His Weekend Soccer Game (and Fans Can’t Believe How Tall He Is)
While Prince William and Kate Middleton have many duties to fulfill as royals , they also enjoy their role as parents to three...
- ProFootball Talk on NBC Sports
Bills receiver Stefon Diggs didn’t have much of a stat line on Sunday night, with three catches for seven yards. However, Diggs racked up a “one” in a very rare category. Diggs wiped out a fan who entered the field, and who apparently was making a beeline for the football. A fan named Carl Fugate [more]
The ongoing saga between Kelly Clarkson and ex Brandon Blackstock over their Montana ranch has finally concluded. It’s an ending that is still somewhat baffling given the fact that the former music manager fought to the bitter end until the pop star gave him a small slice of the property — and honestly, it’s small […]
Beckham announced in November that he planned to convert his salary for this NFL season into bitcoin
- Rolling Stone
The Green Bay Packers quarterback warmed up for his playoff loss by casting doubt on Biden's win. The former president's team is thrilled
Stefon Diggs knocked the shoes off a field invader with a massive hit during the Chiefs-Bills thriller
Stefon Diggs landed a massive hit on the fan who invaded the field during the final minutes of the Chiefs-Bills AFC Divisional thriller Sunday night.
The former president seemed to need some adulation at Mar-a-Lago.
- Democrat and Chronicle
Mahomes dropped his helmet and wrapped his arms around another player on the field. But it wasn't someone in red and gold. It was Josh Allen.
- Best Life
David Cassidy may be one of the top teen idols of all time, but his half-brother Shaun Cassidy was a major heartthrob too. While his older brother starred on The Partridge Family and had a career in pop music, Cassidy led The Hardy Boys Mysteries and a became pop star himself in the latter half of the '70s, with hits including "Da Doo Ron Ron" and "Hey Deanie."Though he got his start in music and acting, Cassidy, now 63, went in a very different direction with his career once he hit adulthood. I
- Best Life
Multiple sclerosis (MS) is a disabling disease of the central nervous system in which the immune system attacks the myelin sheath—a layer of fatty tissue and protein that protects nerve fibers in the brain and spinal cord—causing communication problems between the brain and body. Eventually, this can cause nerve damage, resulting in a whole host of phantom pains and sensations.Historically, MS has been a condition that's shrouded in mystery and often met with dismissal or disbelief, but experts
- Touchdown Wire
The Super Bowl LVI logo, which is supposed to represent palm trees, looks quite a bit more grisly than its artists intended.
- NBC Sports Chicago
Grayson Allen called the controversial flagrant foul he committed on Alex Caruso an "unfortunate" basketball play in a message on his Discord channel.
Salma Hayek is back at it, yet again with a jaw-dropping and sultry beach-themed photo shoot. On Jan 19, Hayek posted two photos of her latest water-based adventure to her Instagram with the caption, “Some people run to visit the fish.” View this post on Instagram A post shared by Salma Hayek Pinault (@salmahayek) In […]
It's two-for-one eco car day in for this environmentalist.
- Chiefs Wire
After the #Bills took the lead with 13 seconds left, #Chiefs HC Andy Reid told Patrick Mahomes: "When it's looking grim, go be the grim reaper."
- NBC Sports Boston
Here's why Tampa Bay Buccaneers quarterback Tom Brady was flagged for unsportsmanlike conduct for the first time in his career in his team's loss to the Los Angeles Rams on Sunday.
- Business Insider
Pilot forced to bail out of F-35 stealth jet after 'landing mishap' on US Navy aircraft carrier in South China Sea
Seven US Navy sailors were injured in the mishap aboard aircraft carrier USS Carl Vinson, the Navy said.