Army and emergency services personnel were drafted in to work on clearing the streets overnight and to support citizens who suffered damage to their homes.
Although hailstorms have hit the city of more than five million people before, they have rarely been this heavy.
Guadalajara had seen temperatures of 30C less than 24 hours before the storm.
“I witnessed scenes that I had never seen before: the hail more than a metre high, and then we ask ourselves if climate change is real,” he wrote on Twitter.
Mr Ramírez added there were no recorded injuries or deaths from the incident.
While children enjoyed the freak storm and hurled ice balls at each other, Civil Protection personnel and soldiers were brought in with heavy machinery to clear the roads.
Early this morning, more extreme weather was predicted off Mexico’s southern coast, as the US National Hurricane Centre said a newly formed tropical storm had gained strength.
The organisation said it was expected to reach hurricane strength but was unlikely to threaten land.