The reunion special will air on the streaming service around Thanksgiving, HBO Max announced on Monday.
Will Smith will star alongside his former cast mates Tatyana Ali, Karyn Parsons, Joseph Marcell, Daphne Maxwell Reid, Alfonso Ribeiro, and DJ Jazzy Jeff.
The reunion is currently scheduled for taping on 10 September, marking the 30th anniversary of the show’s premiere in the US.
HBO MAx, the streaming home of The Fresh Prince of Bel-Air, described the upcoming reunion as “a funny and heartfelt night full of music, dancing, and special surprise guests”.
The sitcom ran for six seasons between 1990 and 1996 and remains a fan favourite to this day.
News of the reunion comes not long after it was announced that the iconic series might be getting a reboot.
The show, which was reportedly being shopped to streamers earlier this month, is based on a fan-based trailer giving the sitcom a new, more dramatic look.