German scientists make paralyzed mice walk again

Scientists have made paralyzed mice walk again

by using a designer protein injected into the brain

CELL BIOLOGIST, MARCO LEIBINGER

"This mouse can actually walk again. We didn't expect that at all back then. We had to check the mice every day. I had taken them out, had them on the hand and suddenly I saw that the two of them were moving very, very strongly. And that actually surprised me. And then I put them on the table and saw that they could actually walk again"

The rodents that received the treatment

started walking after two to three weeks

Scientists hope the experiment

could help treat spinal cord injuries in humans

LEADING SCIENTIST, DR. DIETMAR FISCHER

"In general, results or treatments that you develop in mice can normally not one to one be transferred to human beings. So there is still a lot of work ahead of us that needs to be done. And so right now, we cannot guarantee that it works in humans. But what we did is we at least showed that in principle, functional regeneration can occur after complete spinal cord injury. And I think that's certainly very nice and something we are very happy about."

Video Transcript

- This mouse can actually walk again. We didn't expect that at all back then. We had to check the mice every day. I had taken them out, had them on the hand. And suddenly, I saw that the two of them were moving very, very strongly. And that actually surprised me. And then I put them on the table and saw that they could actually walk again.

- In general, results or treatments that you develop in mice can normally not one to one transfer to human beings. So there is still a lot of work ahead of us that needs to be done. And so right now, we cannot guarantee that it works in humans. But what we did is we at least showed that, in principle, functional regeneration can occur after complete spinal cord injury. And I think that's certainly very nice and something we are very happy about.