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By Caren Bohan, Emily Flitter and Amanda Becker WASHINGTON/NEW YORK/DES MOINES, Iowa (Reuters) - Hillary Clinton, under pressure from the left wing of her Democratic Party to aggressively campaign against income inequality, voiced concern about the hefty paychecks of some corporate executives in an email to supporters. Striking a populist note, Clinton, who announced on Sunday she was running for president in 2016, said American families were still facing financial hardship at a time "when the average CEO makes about 300 times what the average worker makes." In a tightly scripted campaign launch in which there were few surprises, the comments were unexpected, at least by progressives, who saw them as an early sign she may shift away from the centrist economic policies pursued by her husband, former President Bill Clinton. “I definitely see the push from the left wing, which I think is great,” said Jared Milrad, a Clinton supporter who appeared in a video launching her campaign for the presidency. Milrad said he saw the populist rhetoric as a sign that Clinton "has been listening" to backers such as himself who want her to embrace some of the economic policies pushed by Senator Elizabeth Warren, a hero of liberal Democrats. Warren favors tighter regulation of big banks and a bolstering of the social safety net. PAY GAP WIDENING The enthusiasm of some progressives was tempered by the fact that they have yet to see the details of Clinton's policy proposals. “So far we don’t know very much,” said Zephyr Teachout, a one-time New York gubernatorial candidate. “I hope Clinton clarifies where she stands on these issues.” Leo Gerard, international president for the United Steelworkers union, was also guarded. "I think it's too early to make any judgments on what I would call the very short opening statement, and we'll see what happens as we go forward," Gerard told reporters at a conference of the BlueGreen Alliance, a coalition of large labor unions and environmental groups. The gap between the pay of chief executives from major corporations has skyrocketed over the past several decades. In 1965, CEOs earned about 20 times what a typical worker brought home, according to research by the Economic Policy Institute, a liberal think tank. In 2013, CEO compensation was nearly 300 times the pay of the average worker, the EPI study said. Economic inequality has been a top campaign theme for Democrats for the past several years, including for President Barack Obama. While he often talks about the need to address economic inequality, he is frequently cautious about appearing to lash out at corporations and their executives. In 2009, for example, he bashed "fat cat" Wall Street bankers for accepting big pay packages in the aftermath of the 2007-2009 financial crisis at a time when many Americans were suffering hardship. Faced with a barrage of criticism from Republicans, Obama stressed he was not anti-business. Obama's efforts to walk a fine line on economic populism highlight the balancing act that Clinton will face. While such rhetoric stirs enthusiasm on the left, she risks irking wealthy donors, including her backers on Wall Street. Clinton supporters on Wall Street reacted with equanimity on Monday when asked about her vow to level the playing field for the middle class. "She will address inequality. The mistake would be to just assume that that’s populist," said Lynn Forester de Rothschild, the CEO of the family investment company E.L. Rothschild and a Clinton supporter. "If rich people are not worried about today's levels of income inequality, then they are stupid," she said. Paul Beirne, a principal at Bernstein Global Wealth Management who supports Clinton, said there had been some movement toward better accountability in CEO pay, but more work was needed. (Additional reporting by Roberta Rampton in Washington and Jonathan Allen in New York, editing by Ross Colvin)