Holiday Light Displays in Roseville

Holiday Light Displays in Roseville

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  • Biden showed his years of Senate experience by winning a filibuster fight without saying a word

    Analysis: Biden had nothing to gain and everything to lose from fighting a quixotic war over the filibuster just days into his presidency.

  • Pennsylvania teacher fights suspension over DC protest

    One day after the deadly insurrection in Washington, a Pennsylvania school district announced it was suspending a teacher who, the district asserted, “was involved in the electoral college protest that took place at the United States Capitol Building.” Three weeks later, Jason Moorehead is fighting to restore his reputation and resume teaching after he says the Allentown School District falsely accused him of being at the Capitol during the siege. The district says Moorehead’s social media posts about the events of Jan. 6, and not just his presence in Washington that day, are a focus of its probe.

  • The Marines Want a Next-Gen Combat Utility Uniform. Here's What Could Change

    The move could save the service millions of dollars and provide wearers with better protection in the field.

  • Mexican president progressing well with minor symptoms after COVID-19 diagnosis, minister says

    Mexican President Andres Manuel Lopez Obrador was progressing well with minimal symptoms of COVID-19, a senior health official said on Wednesday. Lopez Obrador, 67, was experiencing brief episodes of fever and a minor headache, but "virtually no other discomfort," Deputy Health Minister Hugo Lopez-Gatell said during a regular government news conference. "He is still very active, not only with minimal symptoms, but he continues to carry out his functions," Lopez-Gatell said.

  • Doctor with terminal cancer kills paediatrician in hostage siege a childrens clinic

    A doctor with terminal cancer killed a female paediatrician and then himself after taking hostages at a children's clinic in Austin, Texas. Dr Bharat Narumanchi held hostages in a five-hour siege before killing Dr Katherine Lindley Dodson. Narumanchi had applied for a volunteer position at the clinic a week ago and was declined. He later came back carrying a pistol, a shotgun and two duffel bags. Police spokesman Jeff Greenwalt said Narumanchi had recently been given "weeks to live" after a cancer diagnosis. He said: "The case as far as who did this is closed. We know who did it. And we know that there's no longer a threat to the public. But we really, really want to answer the question of why." Dr Lindley Dodson, 43, was beloved by patients and their families. Karen Vladeck, whose two children were among her patients, told the Austin American-Statesman: "You saw her at your worst when your kid was sick, and she just always had a smile on her face. "She made you feel like you were the only parent there, even though there was a line of kids waiting." During the siege a SWAT team used a megaphone to communicate with the armed doctor. A hostage negotiator shouted: "Your life is very important to me. And I know life is very important to you. "You don't deserve to go through this. For all you have done for others. That is why I want to help you work through this. You have saved a lot of lives." Police first sent in a robot and then officers went into the medical office where they found two bodies. They did not comment on how the two doctors died. A police spokesman said: "The SWAT situation has ended. Two subjects have been located and were pronounced deceased."

  • Biden news – live: Republican Party suffers ‘mass exodus’ as FBI thwarts plot against California governor

    Follow the latest updates

  • Singapore detains 16-year-old over plans to attack mosques

    Authorities in Singapore have detained without trial a 16-year-old student who made detailed plans and preparations to carry out “terrorist attacks” on two mosques with a machete. The Singaporean teen was inspired by an Australian white supremacist who killed 51 worshippers at two mosques in New Zealand in 2019, the Internal Security Department said Wednesday. The teen detained in December was the youngest terror suspect to be held under the country's Internal Security Act, it added.

  • Here Are The Brightest Decor Buys of the Season

    Let’s get loudOriginally Appeared on Architectural Digest

  • Top U.S. Capitol security officials apologize for 'failings' in Jan. 6 attack

    Top U.S. Capitol security officials apologized on Tuesday for "failings" during the deadly attack on the building by followers of then-President Donald Trump in a bid to stop the certification of Joe Biden's election victory. "I am here to offer my sincerest apologies on behalf of the Department," said Yogananda Pittman, the acting chief of Capitol Police, according to a prepared statement for the U.S. House of Representatives' Appropriations Committee. About one dozen officials from agencies including the FBI, National Guard, Justice Department and U.S. Capitol Police briefed House appropriators who are looking into the events of Jan. 6.

  • Former Obama speechwriter "preemptively frustrated" with Biden's unity efforts

    President Obama's former speechwriter says he's "preemptively frustrated" with President Biden's effort to find unity with Republicans.What they're saying: Cody Keenan told Axios that Biden's messaging team has "struck all the right chords," but at some point "they're gonna have to answer questions like, 'Why didn't you achieve unity?' when there's an entire political party that's already acting to stop it."Get smarter, faster with the news CEOs, entrepreneurs and top politicians read. Sign up for Axios Newsletters here.Keenan spent 14 years writing for Obama, including working alongside Biden for eight of those years. He acknowledged being embittered by his own experience, especially after Sen. Mitch McConnell pledged to make his former boss a one-term president. * "Until the Republican Party steps up and tells their own voters what's really happening with the truth, it's going to be elusive," Keenan said. "It's not up to (President Biden) alone to deliver. He can't."Keenan helped Obama with the first volume of his memoir, "A Promised Land." He stopped working with the former president on New Year's Eve and has taken a full-time role at Fenway Strategies. The firm is run by another ex-Obama speechwriter — Jon Favreau — and presidential aide, Tommy Vietor. * "It just seemed like a natural spot after the book and the elections and, you know, [Obama] is not going to do a ton, especially with Biden in office," Keenan said.Keenan is also writing a book, titled "Grace," about the 10 days from the 2015 shooting at a historic Black church in Charleston, South Carolina, to the eulogy Obama delivered for Rev. Clementa Pinckney. * Obama ended by singing "Amazing Grace." * The title also nods to Keenan's newborn daughter, named Grace.Support safe, smart, sane journalism. Sign up for Axios Newsletters here.

  • Mike Pence is homeless after leaving office and ‘couch-surfing’ with Indiana politicians, report says

    Mike Pence has been residing in public housing for the past eight years

  • Why it takes 2 shots to make mRNA vaccines do their antibody-creating best – and what the data shows on delaying the booster dose

    After a second dose of the COVID-19 mRNA vaccine, a swarm of antibodies attacks the virus. Kateryna Kon/Science Photo Library via Getty ImagesWith the U.S. facing vaccination delays because of worker shortages and distribution problems, federal health officials now say it’s OK to push back the second dose of the two-part vaccine by as much as six weeks. As an infectious disease doctor, I’ve been fielding a lot of questions from my patients as well as my friends and family about whether the COVID-19 vaccine will still work if people are late receiving their second dose. Why you need two doses 3-4 weeks apart Two doses, separated by three to four weeks, is the tried-and-true approach to generate an effective immune response through vaccination, not just for COVID but for hepatitis A and B and other diseases as well. The first dose primes the immune system and introduces the body to the germ of interest. This allows the immune system to prepare its defense. The second dose, or booster, provides the opportunity for the immune system to ramp up the quality and quantity of the antibodies used to fight the virus. In the case of the Pfizer and Moderna COVID-19 vaccines, the second dose increases the protection afforded by the vaccine from 60% to approximately 95%. Why the CDC decided receiving the second dose within 42 days is OK In the clinical trial, the second dose of the Pfizer vaccine was administered as early as day 19 and as late as day 42 to 93% of the subjects. Since protection was approximately 95% for everyone who was vaccinated within this time “window,” there is little reason not to allow some flexibility in the timing of the second dose 2. As more vaccine becomes available, the timing of the second dose should be close to four weeks for the Pfizer and Moderna vaccines. But the good news is that even while supplies remain limited, the science suggests that there’s nothing bad about getting a second dose as late as 42 days after the first. What the immune system does between the first and second dose The biology through which the mRNA vaccines induce their protection from COVID-19 is fundamentally different from that with other vaccines. Pfizer and Moderna vaccines use messenger RNA that encodes the spike glycoprotein. Upon injection of the vaccine, the mRNA enters into immune cells called dendritic cells. The dendritic cells use the instructions written in the mRNA to synthesize the hallmark spike glycoprotein, which characterizes the SARS-CoV-2 virus that causes COVID-19. These immune cells then show the spike glycoprotein to B-cells, which then make anti-spike antibodies. Dendritic cells recognize viruses and present information about the spike protein to T-cells. T-cells provide information about the viral spike protein to B-cells, which are transformed to memory B-cells that store information about the virus. When this memory B-cell is activated with an infection or the second dose of the vaccine, this causes some of the B-cells to change into plasma B-cells that secrete protective antibodies that fight the virus. Kateryna Kon/Science Photo Library via Getty Images The mRNA vaccines are uniquely capable of inducing a special kind of immune cell – called a T-follicular helper cell – to help B-cells produce antibodies. The T-cells do this through direct contact with the B-cells and by sending chemical signals that tell the B-cells to produce antibodies. It is this help in antibody production that makes these vaccines so effective. But not all B-cells are the same. There are two kinds that make anti-spike antibodies: long-lived plasma cells and memory B-cells. The long-lived plasma cells, as their name implies, live in the bone marrow for years after vaccination, continuously churning out antibody – in this case anti-spike antibody. These long-lived B-cells do not need to be boosted. The memory B-cells, on the other hand, live in a state akin to hibernation. They do not produce antibodies until stimulated by a booster of the vaccine, or are exposed to infection with the coronavirus that causes COVID-19. That is the reason we need that second dose. Together these two types of B-cells provide a constant level of protection. What happens if you don’t get the Pfizer or Moderna second dose on time? With current vaccine shortages, and problems with setting up the infrastructure to vaccinate millions of people, many physicians are concerned that the second dose of vaccine won’t be delivered in the prescribed three-to-four-week window. That booster shot is necessary for the T-cells to stimulate the memory B-cells to produce massive quantities of antibodies. If the booster isn’t given within the appropriate window, lower quantities of antibodies will be produced that may not provide as powerful protection from the virus. [Deep knowledge, daily. Sign up for The Conversation’s newsletter.]This article is republished from The Conversation, a nonprofit news site dedicated to sharing ideas from academic experts. It was written by: William Petri, University of Virginia. Read more:How mRNA vaccines from Pfizer and Moderna work, why they’re a breakthrough and why they need to be kept so coldCOVID-19 vaccines were developed in record time – but are these game-changers safe? William Petri receives research funding from the NIH, the Bill & Melinda Gates Foundation and Regeneron, Inc.

  • Exclusive: Proud Boys leader was ‘prolific’ informer for law enforcement

    Enrique Tarrio, the leader of the Proud Boys extremist group, has a past as an informer for federal and local law enforcement, repeatedly working undercover for investigators after he was arrested in 2012, according to a former prosecutor and a transcript of a 2014 federal court proceeding obtained by Reuters. In the Miami hearing, a federal prosecutor, a Federal Bureau of Investigation agent and Tarrio’s own lawyer described his undercover work and said he had helped authorities prosecute more than a dozen people in various cases involving drugs, gambling and human smuggling. Tarrio, in an interview with Reuters Tuesday, denied working undercover or cooperating in cases against others.

  • Israel: 900 Holocaust survivors died of COVID-19 in 2020

    The bureau reported that about 5,300 survivors of the World War II-era mass murder of European Jews and other groups by the Nazis were infected in 2020 with the coronavirus. About 17% of those Holocaust survivors died of the virus, similar to the percentage of others of the same age. All Holocaust survivors are at least 75 years old and COVID-19, the illness caused by the virus, is especially lethal to seniors.

  • Biden’s new sign language interpreter runs a right-wing Facebook group and has been pictured in a MAGA hat

    One video featuring Heather Mewshaw is titled ‘Joe Biden is literally and legally not the President elect’

  • China warns Taiwan that 'independence means war’

    China toughened its language toward Taiwan on Thursday, warning after recent stepped-up military activities near the island that "independence means war" and that its armed forces were taking action to respond to provocation and foreign interference.

  • AstraZeneca to ask Japan's JCR Pharmaceutical to produce COVID-19 vaccine - Nikkei

    AstraZeneca Plc will license Japanese biotechnology company JCR Pharmaceutical, to produce some 90 million doses of its COVID-19 vaccine to help Japan avoid shortages and delays, the Nikkei newspaper reported. The government in December agreed to buy 120 million doses of the vaccine developed by AstraZeneca and Oxford University with deliveries to begin in May, the Nikkei said. Officials at JCR Pharmaceuticals and AstraZeneca's Japan unit were not immediately available for comment outside business hours on Wednesday.

  • India says China ties at crossroads amid border standoff

    India on Thursday said its relationship with China is at a crossroads with the months-old military standoff in mountainous border areas profoundly disturbing the ties. “Peace and tranquillity in the border areas is the basis for the development of relations in other domains,” External Affairs Minister Subrahmanyam Jaishankar said in a speech at a conference discussing India-China ties. Indian and Chinese soldiers brawled again last week in the Naku La area of northeastern Sikkim state.

  • Grandmother ‘overjoyed’ to be outside after receiving Covid-19 vaccine killed in Portland vehicle attack

    Police have not released a motive in the attack

  • Have a Drink in Style with These 9 Cocktail Tables

    The best occasional tables keep your cocktail at arm’s reachOriginally Appeared on Architectural Digest