Which team will get the victory?
The Colts are an 8.5-point favorite in the game, according to Tipico Sportsbook.
The Colts are -420 on the money line and the Texans are +320.
The over/under for the game is set at 45.5 points.
Pro Football Network: Colts 27, Texans 10
Ben Rolfe writes: "The Texans are one of the most confusing teams in the NFL this season. They played up to the Titans and Patriots but were just beaten by a bad Jets team. The Colts won the last meeting comfortably, and the Texans’ run defense will be extremely susceptible to the talents of Jonathan Taylor."
Sportsnaut: Colts 34, Texans 10
Matt Johnson writes: "The Houston Texans are the worst team in the NFL ... Wentz should have no trouble against Houston’s secondary and Jonathan Taylor will power through and run circles around the defense. If Indianapolis doesn’t get two double-digit victories over the Colts in 2021, it would be a disappointment."
Draft Kings: Colts will cover against Texans in Week 13
Teddy Ricketson writes: "This season has been wild enough already that it truly wouldn’t surprise me if somehow the Texans came away with a win here. But, for this article, we are going with the more likely of outcomes. The Colts' offense, mainly Jonathan Taylor, has looked solid the last few weeks and their defense should be able to stave off the efforts of Tyrod Taylor and Brandin Cooks. The Colts won the first iteration of this AFC South divisional matchup back in Week 6 by a score of 31-3. Kind of surprised the line isn’t bigger here. Colts cover!"
Fansided: Take the Colts to cover vs. Texans
Matt De Saro writes: "Jonathan Taylor is the key to a quick and easy won over the Texans. Houston ranks 24th in the NFL in opponent yards per rush and 31st with 135.6 rushing yards surrendered per game. Taylor was bottled up in last week’s loss and will be hungry to get back over 100 yards rushing for the fourth time in six games."
Sportsnaut: Colts 36, Texans 13
Andrew Buller-Russ writes: "About the only chance the Texans have here is if Tyrod Taylor has a huge game and if the Houston D can find a way to limit Jonathan Taylor. The odds don’t look good."
FiveThirtyEight.com: Colts have a 77% win probability
The site fives the Texans a 23% win probability in the NFL Week 13 game.
ESPN: Colts have a 75.7% chance to win
The site's Football Power Index gives the Colts a 24.1% chance to pick up the victory in the Week 13 NFL game.
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This article originally appeared on Arizona Republic: Indianapolis Colts vs. Houston Texans picks, odds NFL Week 13 game