Israel bombed the home of the Hamas chief in Gaza early on Sunday, as hostilities stretched into a seventh day with no signs of stopping soon.
The sounds of heavy bombardment across the coastal enclave roared through the night.
According to Hamas television, Yehya Al-Sinwar's home was targeted.
He's led the military and political wings of Hamas in Gaza since 2017.
Meanwhile, Israelis in Tel Aviv and Beersheba dashed for bomb shelters as sirens blared, warning of incoming rocket fire.
Israel has recorded 10 deaths, while health officials in Gaza have reported at least 148 people killed since the violence began last week.
Both Israel and Hamas have insisted they would continue their cross-border fire, a day after Israel destroyed a 12-story media building in Gaza City, which housed an Associated Press and Al Jazeera bureau.
Israeli Prime Minister Benjamin Netanyahu said late on Saturday that their offensive will continue for as long as necessary.
"We will continue to act with full force. we are hitting the terrorist organisation with crushing blows. Whoever lit the fire, will receive fire."
The United Nations Security Council is due to meet later on Sunday to discuss ways to restore calm.