Letters: Effectiveness of Alzheimer's drug in question

Letters to the editor
·2 min read

Regarding the Aug. 17 op-ed, "Flawed legislation blocks Alzheimer's research, cures": Although I very much agree with U.S. Rep. Brad Wenstrup regarding the need for finding a treatment for Alzheimer’s, I think it is important to note that the drug he is discussing has questionable effectiveness in treating the disease. Two large studies looked into the effectiveness of the drug, and, whereas, one found that high doses slightly slowed, but did not stop or reverse, the disease progression, the other study did not show a benefit and was stopped early.

Although the Food and Drug Administration advisory panel did not approve the drug, the agency did decide to grant conditional approval and gave Biogen, the company which makes the drug, nine years to confirm the drug’s possible benefit. There is much division among doctors and medical institutions regarding the use of the drug. There are likewise significant side effects, including cerebral hemorrhage and swelling.

It is important to look at all of the data in attempting to understand utilization and reimbursement issues.

Igor Dumbadze, MD, Hyde Park

Despite controversy, the streetcar is an asset to Cincinnati

I have now ridden on the Downtown streetcar twice and found it to not only to be extremely helpful but pleasurable as well. I saw people commuting to and from work and others like myself just enjoying the sights of Cincinnati. I know there was considerable controversy regarding its construction, but I consider it a very significant and practical addition to the city. The fact it is entirely free is just the cherry on top.Elizabeth Kromer, Mason

Treatment of heroic veteran and photographer was shameful

Referencing the Aug. 11 article, "Cincinnati photographer got great views of cities, not-so-great views of justice system": Isaac Wright has gifted this community with inspiring and beautiful works of art that will be appreciated for decades to come. Sadly, the role played by Hamilton County in this heroic veteran's odyssey is one of utter contempt and shame, not unlike the inquisitors who imprisoned John Bunyan when he wrote literature's first novel. Wouldn't it be nice if our community could be remembered for something more elevated than the hero's foil for a change.

Douglas J. May, Montgomery

This article originally appeared on Cincinnati Enquirer: Letters: Effectiveness of Alzheimer's drug in question