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- Yahoo News
Congress prepares for major fight over voting laws in the wake of Trump's false fraud claims
Former President Donald Trump’s “big lie” about a stolen election may have been discredited over and over in the courts, and disgraced by the attack on the U.S. Capitol, but the corrosive effect of his dishonesty will linger on, complicating efforts to strengthen American elections.
- NBC News
Biden showed his years of Senate experience by winning a filibuster fight without saying a word
Analysis: Biden had nothing to gain and everything to lose from fighting a quixotic war over the filibuster just days into his presidency.
- Associated Press
Iran's president criticizes prosecution of telecom minister
Iranian President Hassan Rouhani on Wednesday criticized Iran's hard-liner dominated judiciary over last week's prosecution of the countrys telecommunications minister. Mohammad Javad Azari Jahromi was released on bail after he was summoned for prosecution. Judiciary officials cited his refusal to block Instagram and impose limitations on the bandwidth of other foreign social media and messaging systems.
- The Telegraph
Doctor with terminal cancer kills paediatrician in hostage siege a childrens clinic
A doctor with terminal cancer killed a female paediatrician and then himself after taking hostages at a children's clinic in Austin, Texas. Dr Bharat Narumanchi held hostages in a five-hour siege before killing Dr Katherine Lindley Dodson. Narumanchi had applied for a volunteer position at the clinic a week ago and was declined. He later came back carrying a pistol, a shotgun and two duffel bags. Police spokesman Jeff Greenwalt said Narumanchi had recently been given "weeks to live" after a cancer diagnosis. He said: "The case as far as who did this is closed. We know who did it. And we know that there's no longer a threat to the public. But we really, really want to answer the question of why." Dr Lindley Dodson, 43, was beloved by patients and their families. Karen Vladeck, whose two children were among her patients, told the Austin American-Statesman: "You saw her at your worst when your kid was sick, and she just always had a smile on her face. "She made you feel like you were the only parent there, even though there was a line of kids waiting." During the siege a SWAT team used a megaphone to communicate with the armed doctor. A hostage negotiator shouted: "Your life is very important to me. And I know life is very important to you. "You don't deserve to go through this. For all you have done for others. That is why I want to help you work through this. You have saved a lot of lives." Police first sent in a robot and then officers went into the medical office where they found two bodies. They did not comment on how the two doctors died. A police spokesman said: "The SWAT situation has ended. Two subjects have been located and were pronounced deceased."
- Reuters
Ghislaine Maxwell seeks dismissal of criminal case, cites Epstein agreement
Ghislaine Maxwell asked a U.S. judge to dismiss the criminal case accusing her of recruiting teenage girls for Jeffrey Epstein to sexually abuse, citing various grounds including that an agreement not to prosecute the late financier also shielded her. In court filings on Monday night, lawyers for the British socialite also complained that not enough Black and Hispanic grand jurors were used to indict her, and that parts of the indictment were too vague and should be thrown out. A spokesman for U.S. Attorney Audrey Strauss in Manhattan declined to comment on Tuesday.
- Architectural Digest
Here Are The Brightest Decor Buys of the Season
Let’s get loudOriginally Appeared on Architectural Digest
- The Independent
Biden news – live: Republican Party suffers ‘mass exodus’ as FBI thwarts plot against California governor
Follow the latest updates
- Associated Press
Alaska to investigate issuance of offensive license plate
An Alaska department plans to investigate the issuance of “3REICH” personalized license plates, while a spokesperson for Gov. Mike Dunleavy said Dunleavy removed a member of Alaska's Human Rights Commission for comments she made about the controversy. The issue drew attention after a former newspaper editor, Matt Tunseth, posted a picture of the plate on social media. Debate over the issue gained traction on social media and blogs over the weekend, and Department of Administration Commissioner Kelly Tshibaka announced Monday that she was ordering a review of Division of Motor Vehicles' processes to determine how the plates were issued.
- The Conversation
Why it takes 2 shots to make mRNA vaccines do their antibody-creating best – and what the data shows on delaying the booster dose
After a second dose of the COVID-19 mRNA vaccine, a swarm of antibodies attacks the virus. Kateryna Kon/Science Photo Library via Getty ImagesWith the U.S. facing vaccination delays because of worker shortages and distribution problems, federal health officials now say it’s OK to push back the second dose of the two-part vaccine by as much as six weeks. As an infectious disease doctor, I’ve been fielding a lot of questions from my patients as well as my friends and family about whether the COVID-19 vaccine will still work if people are late receiving their second dose. Why you need two doses 3-4 weeks apart Two doses, separated by three to four weeks, is the tried-and-true approach to generate an effective immune response through vaccination, not just for COVID but for hepatitis A and B and other diseases as well. The first dose primes the immune system and introduces the body to the germ of interest. This allows the immune system to prepare its defense. The second dose, or booster, provides the opportunity for the immune system to ramp up the quality and quantity of the antibodies used to fight the virus. In the case of the Pfizer and Moderna COVID-19 vaccines, the second dose increases the protection afforded by the vaccine from 60% to approximately 95%. Why the CDC decided receiving the second dose within 42 days is OK In the clinical trial, the second dose of the Pfizer vaccine was administered as early as day 19 and as late as day 42 to 93% of the subjects. Since protection was approximately 95% for everyone who was vaccinated within this time “window,” there is little reason not to allow some flexibility in the timing of the second dose 2. As more vaccine becomes available, the timing of the second dose should be close to four weeks for the Pfizer and Moderna vaccines. But the good news is that even while supplies remain limited, the science suggests that there’s nothing bad about getting a second dose as late as 42 days after the first. What the immune system does between the first and second dose The biology through which the mRNA vaccines induce their protection from COVID-19 is fundamentally different from that with other vaccines. Pfizer and Moderna vaccines use messenger RNA that encodes the spike glycoprotein. Upon injection of the vaccine, the mRNA enters into immune cells called dendritic cells. The dendritic cells use the instructions written in the mRNA to synthesize the hallmark spike glycoprotein, which characterizes the SARS-CoV-2 virus that causes COVID-19. These immune cells then show the spike glycoprotein to B-cells, which then make anti-spike antibodies. Dendritic cells recognize viruses and present information about the spike protein to T-cells. T-cells provide information about the viral spike protein to B-cells, which are transformed to memory B-cells that store information about the virus. When this memory B-cell is activated with an infection or the second dose of the vaccine, this causes some of the B-cells to change into plasma B-cells that secrete protective antibodies that fight the virus. Kateryna Kon/Science Photo Library via Getty Images The mRNA vaccines are uniquely capable of inducing a special kind of immune cell – called a T-follicular helper cell – to help B-cells produce antibodies. The T-cells do this through direct contact with the B-cells and by sending chemical signals that tell the B-cells to produce antibodies. It is this help in antibody production that makes these vaccines so effective. But not all B-cells are the same. There are two kinds that make anti-spike antibodies: long-lived plasma cells and memory B-cells. The long-lived plasma cells, as their name implies, live in the bone marrow for years after vaccination, continuously churning out antibody – in this case anti-spike antibody. These long-lived B-cells do not need to be boosted. The memory B-cells, on the other hand, live in a state akin to hibernation. They do not produce antibodies until stimulated by a booster of the vaccine, or are exposed to infection with the coronavirus that causes COVID-19. That is the reason we need that second dose. Together these two types of B-cells provide a constant level of protection. What happens if you don’t get the Pfizer or Moderna second dose on time? With current vaccine shortages, and problems with setting up the infrastructure to vaccinate millions of people, many physicians are concerned that the second dose of vaccine won’t be delivered in the prescribed three-to-four-week window. That booster shot is necessary for the T-cells to stimulate the memory B-cells to produce massive quantities of antibodies. If the booster isn’t given within the appropriate window, lower quantities of antibodies will be produced that may not provide as powerful protection from the virus. [Deep knowledge, daily. Sign up for The Conversation’s newsletter.]This article is republished from The Conversation, a nonprofit news site dedicated to sharing ideas from academic experts. It was written by: William Petri, University of Virginia. Read more:How mRNA vaccines from Pfizer and Moderna work, why they’re a breakthrough and why they need to be kept so coldCOVID-19 vaccines were developed in record time – but are these game-changers safe? William Petri receives research funding from the NIH, the Bill & Melinda Gates Foundation and Regeneron, Inc.
- Reuters
AstraZeneca to ask Japan's JCR Pharmaceutical to produce COVID-19 vaccine - Nikkei
AstraZeneca Plc will license Japanese biotechnology company JCR Pharmaceutical, to produce some 90 million doses of its COVID-19 vaccine to help Japan avoid shortages and delays, the Nikkei newspaper reported. The government in December agreed to buy 120 million doses of the vaccine developed by AstraZeneca and Oxford University with deliveries to begin in May, the Nikkei said. Officials at JCR Pharmaceuticals and AstraZeneca's Japan unit were not immediately available for comment outside business hours on Wednesday.
- The Independent
Mike Pence is homeless after leaving office and ‘couch-surfing’ with Indiana politicians, report says
Mike Pence has been residing in public housing for the past eight years
- The Week
John Kerry: American workers 'fed a false narrative' that shift to clean energy is 'coming at their expense'
President Biden on Wednesday turned his attention to climate issues, signing executive orders that seek to halt new oil and gas leases on public lands and waters, conserve 30 percent of federal lands and waters by 2030, and find ways to double wind production by the same year. John Kerry, the first-ever United States Climate Envoy, championed the actions, reiterating his belief that the climate crisis is "existential" and "failure, literally, is not an option." While briefing reporters, Kerry was asked about potential job losses in the fossil fuel industry, and whether he had a message for workers who believe they are witnessing the end of their livelihoods. Kerry explained that those workers "have been fed a false narrative" by the Trump administration about the shift to clean energy, which he said will not come "at their expense." He added that, before the COVID-19 pandemic, the solar and wind energy industries were growing swiftly, while coal plants have been closing over the last few decades. "The same people can do those jobs. But the choice of doing the solar power one now is a better choice," he said, also pointing out the health risks associated with coal mining. John Kerry says oil and gas workers have been fed a "false narrative" that action on climate change will hurt their livelihoods, and that President Biden wants to "make sure that those folks have better choices" for jobs in the energy sector https://t.co/Nj065CIsxp pic.twitter.com/czkjomesi8 — CBS News (@CBSNews) January 27, 2021 Republicans like Sen. Tom Cotton (R-Ark.) weren't buying the reassurance, suggesting that Kerry's statement lacked empathy, although he didn't explicitly refute the notion that an industry transition may be feasible for fossil fuel workers. John Kerry's message to the tens of thousands of Americans who lost their jobs thanks to the Biden administration: go make solar panels. Where is the empathy that Joe Biden promised in his inauguration? https://t.co/CvQovUlEoD — Tom Cotton (@TomCottonAR) January 27, 2021 More stories from theweek.comBiden is not going to get his $1.9 trillion stimulus plan. And that's okay.5 brutally funny cartoons about the GOP's Trump problemWith Senate Republicans balking at convicting Trump, Democrats explore alternative censures
- Reuters Videos
Stakes on climate change couldn't be higher: Kerry
"President Biden is deeply committed...that's why he rejoined the Paris agreement so quickly because he knows it is urgent," Kerry said during a White House briefing. "I think that workers are going to see with the efforts by the Biden administration they are going to have a much better set of choices and frankly it'll create more jobs than stuck where we were," Kerry added.
- Associated Press
Singapore detains 16-year-old over plans to attack mosques
Authorities in Singapore have detained without trial a 16-year-old student who made detailed plans and preparations to carry out “terrorist attacks” on two mosques with a machete. The Singaporean teen was inspired by an Australian white supremacist who killed 51 worshippers at two mosques in New Zealand in 2019, the Internal Security Department said Wednesday. The teen detained in December was the youngest terror suspect to be held under the country's Internal Security Act, it added.
- Reuters
Secretary of State Blinken says U.S. committed to Israel's security
Blinken, in a call with Israeli Foreign Minister Gabi Ashkenazi, applauded recent progress made with the "Abraham Accords" and affirmed U.S. interest in building further on that progress, the U.S. State Department said in a statement. "Foreign Minister Ashkenazi and Secretary Blinken acknowledged the steadfast partnership between the United States and Israel, and that the two countries would work closely together on challenges ahead," it said. The so-called Abraham Accords is a U.S.-brokered agreement to normalize diplomatic ties between Israel and Arab and Muslim countries.
- The Independent
Jill Biden spent her first week as First Lady reshaping the role. Melania Trump spent hers isolated in a tower
New first lady signals she will be an active and constant presence in the White House - drawing stark contrasts to her predecessor
- BBC
Joe Biden's tech - what can the president use?
From the ObamaPad to Joe Biden's Apple Watch and Peloton, being president can be a tech challenge.
- Associated Press
Feds withheld info on virus cases following executions
At least two journalists tested positive for coronavirus after witnessing the Trump administration's final three federal executions, but the Bureau of Prisons knowingly withheld the diagnoses from other media witnesses and did not perform any contact tracing, The Associated Press has learned. The AP is not identifying the journalists, but has confirmed they both received positive coronavirus tests following the executions earlier this month at the Federal Correctional Complex in Terre Haute, Indiana. The Bureau of Prisons just completed a record number of executions under former President Donald Trump, more than any previous administration.
- Time
Putting Harriet Tubman on the $20 Bill Is Not a Sign of Progress. It's a Sign of Disrespect
A congressional staffer departs holding a visual aid following a news conference regarding the redesigned $20 bill meant to honor Harriet Tubman, on Capitol Hill in Washington, D.C., on June 18, 2019. The Biden Administration announced its plan to return to an Obama-era initiative to put Harriet Tubman’s face on the U.S. $20 bill. Her image would replace Andrew Jackson, the notoriously racist President, known both for owning hundreds of slaves and for his brutal and genocidal policy of Indian removal. Based on current designs, a statue of Jackson would remain on the back of the bill, while Harriet Tubman would grace the front.
- The Independent
Grandmother ‘overjoyed’ to be outside after receiving Covid-19 vaccine killed in Portland vehicle attack
Police have not released a motive in the attack