They face Chelsea, with the Blues in fifth and the Reds sixth at the start of the day’s matches - but a win for either would put them into fourth, with West Ham not playing this midweek.
FOLLOW LIVE: Liverpool vs Chelsea – Latest updates
Early in the season the Reds won the reverse clash 2-0 at Stamford Bridge, with Sadio Mane netting both goals after Andreas Christensen was sent-off for the Blues, who were then under Frank Lampard.
Here’s everything you need to know ahead of the game.
When is the match?
The game kicks off at 8:15pm on Thursday 4 March.
Where can I watch it?
The match will be shown live on Sky Sports’ Main Event and Premier League channels, and Sky Sports subscribers can live stream the game online via the SkyGo app.
If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription.
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Confirmed line ups
LFC: Alisson, Alexander-Arnold, Kabak, Fabinho, Robertson, Wijnaldum, Jones, Thiago, Mane, Salah, Firmino
CFC: Mendy, Azpilicueta, Christensen, Rudiger, James, Jorginho, Kante, Chilwell, Ziyech, Mount, Werner
Fabinho’s return would be a major boost for Liverpool and Klopp knows they cannot afford another defeat if they are to make it into the top four. For Chelsea, a draw would be a decent result. Liverpool 1-1 Chelsea.
Liverpool – 6/5
Draw – 13/5
Chelsea – 21/10