Louisville drops ACC matchup to Florida State football: Video highlights from home opener

Louisville football returns to Cardinal Stadium on Friday night with Scott Satterfield and the Cardinals looking to beat Florida State for the third time in a row.

The Atlantic Coast Conference matchup between U of L (1-1) and the Seminoles (2-0) is scheduled to kick off at 7:30 p.m. on ESPN.

After a disastrous season-opening loss at Syracuse, Louisville responded with a comeback victory at the University of Central Florida on Sept. 9. The Cardinals will try to stay undefeated against opponents from the Sunshine State in front of the first home crowd of the season with a Week 4 matchup vs. South Florida looming.

Adding to the excitement surrounding the home opener, U of L legend Michael Bush will be in attendance Friday night as the Cardinals honor the former running back's No. 19 jersey. A Louisville native who starred at Male High School, Bush amassed 2,508 yards and 39 playing for his hometown school from 2003-06.

Florida State heads into town fresh off a bye week. Coach Mike Norvell's undefeated Seminoles are playing in their first ACC game after blowing out Duquesne on Aug. 27 and winning a nail-biter against LSU in New Orleans during Labor Day weekend.

Here's how you can watch and/or listen to Louisville vs. Florida State, and follow along with live updates from Cardinal Stadium below. Once the game starts, check back in for video highlights of all the top plays.

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Be sure to hit REFRESH for the latest updates.

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FINAL: Florida State defeats Louisville 35-31

What a game. Louisville had a chance at the end but couldn't take advantage. Malik Cunningham finished with 243 passing yards (21 for 34) and 127 rushing yards (17 carries).

FSU picks off Malik Cunningham - 0:52, Q4

Malik Cunningham was picked off by Kevin Knowles II. That will do it.

Florida State 35, Louisville 31

Florida State fails to extend its lead, misses field goal - 1:44, Q4

Que the "so you're telling me there's a chance" gif from "Dumb and Dumber."

FSU kicker Ryan Fitzgerald missed another one. This time, it was a 36-yard attempt that went wide left.

Florida State 35, Louisville 31

Florida State takes back the lead against Louisville - 7:54, Q4

Johnny Wilson caught a 2-yard pass from Tate Rodemaker. The Cards have plenty of time to answer, but will they?

Florida State 35, Louisville 31

Louisville is back in front after a field goal - 11:45, Q4

Louisville kicker James Turner gave the Cards a lead with a 36-yard field goal.

Louisville 31, Florida State 28

Tate Rodemaker tosses a touchdown to tie things up - 13:24, Q4

This may shock you, but we are tied again. For the fourth time, things are even between Louisville and Florida State.

Johnny Wilson caught a 10-yard touchdown pass from Tate Rodemaker.

Louisville 28, Florida State 28

Yasir Abdullah and YaYa Diaby get a sack for Louisville - 14:11, Q4

The pair of Louisville defensive players have had impressive nights so far. Earlier in the night, Yasir Abdullah intercepted a pass while YaYa Diaby had another sack.

Malik Cunningham does it again and runs in for a touchdown - 14:25, Q4

Louisville has the lead once again. This time, Louisville quarterback Malik Cunningham scrambled 18 yards for a touchdown. Cunningham has 151 yards through the air and 115 yards on the ground.

Louisville 28, Florida State 21

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End of the third quarter: Louisville 21, Florida State 21

Louisville will start the fourth quarter on Florida State's 23-yard line.

Game attendance announced for Louisville vs FSU

Louisville's Dezmond Tell sacks Tate Rodemaker - 4:21, 3Q

Louisville defensive lineman Dezmond Tell sacked FSU quarterback Tate Rodemaker to force the Seminoles to punt.

Louisville 21, Florida State 21

FSU ties it up with a rushing touchdown - 8:58, 3Q

Even with Jordan Travis out of the game, Florida State found a way to move the ball against Louisville. Running back Lawrance Toafili brought FSU back into the game with a 15-yard rushing touchdown.

Louisville 21, Florida State 21 

Florida State's Jordan Travis will not return after injury

Jordan Travis, the former Louisville quarterback, will not return for FSU, an announcement before halftime concluded noted.

Louisville football leads Florida State at halftime - Louisville 21, FSU 14

Malik Cunningham has completed 13 of his 18 pass attempts for 148 yards and a touchdown. Jawar Jordan has ran 12 times for 71 yards. Trevion Cooley has a rushing and receiving touchdown.

Yasir Abdullah intercepts Tate Rodemaker - 0:33, Q2

Louisville's Yasir Abdullah picked off Florida State's Tate Rodemaker to give the Cards the ball at the 50-yard line.

Florida State forces a Louisville fumble - 1:37, Q2

After an extensive review, it was determined Louisville's Jawhar Jordan fumbled. FSU will take over at the Louisville 48-yard line.

Louisville 21, Florida State 14

Florida State's Jordan Travis injured, taken to the locker room - 4:21, Q2

Under pressure by Louisville's YaYa Diaby, FSU's Jordan Travis grabbed his left leg after hitting the turf. Travis threw what appeared to be an interception at first, but the play was ruled a sack since Travis' knee was down.

Tate Rodemaker is in for Florida State.

Louisville 21, Florida State 14

Trevion Cooley puts Louisville ahead with a touchdown - 5:30, Q2

Louisville has taken back the lead. Trevion Cooley punched in a 1-yard touchdown run. The drive lasted six plays and 43 yards.

Louisville 21, Florida State 14

Louisville gets the ball back on an interception - 9:51, Q2

U of L's Rance Conner picked off Jordan Travis to give Louisville momentum.

Louisville 14, Florida State 14

Malik Cunningham fumbles in FSU's red zone - 10:30, Q2

The drive lasted 13 plays and 65 yards for Louisville, but it ended in a Malik Cunningham fumble that was recovered by Florida State.

Louisville 14, Florida State 14

End of the first quarter - Louisville 14, Florida State 14

Florida State comes right back with a touchdown of its own - 0:15, Q1

And we're tied yet again. This time around, Jordan Travis threw a 21-yard touchdown to Malik McClain. Travis has completed all 11 of his pass attempts for 148 yards.

Louisville 14, Florida State 14

Malik Cunningham connects with Trevion Cooley for a touchdown - 1:23, Q1

On 3rd and 5, Malik Cunningham tossed a 17-yard touchdown to Trevion Cooley to help Louisville take the lead. Cunningham has 85 yards passing and 22 yards on the ground.

Louisville 14, Florida State 7

Florida State misses a field goal, stays tied with Louisville - 3:40, Q1

Wide right! FSU kicker Ryan Fitzgerald attempted a 37-yard field goal, but the kick went right of the goal post.

Louisville 7, Florida State 7

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Louisville ties it up with a Malik Cunningham run - 8:28, Q1

And we have a ball game. Malik Cunningham capped a seven-play, 75-yard drive with an 8-yard touchdown run.

Louisville 7, Florida State 7

Tiyon Evans is also out for Louisville against Florida State

The Cardinals are without Tiyon Evans and Jalen Mitchell tonight.

A Louisville spokesperson confirmed Evans's absence a few hours prior to kickoff. But Mitchell's absence was not announced and broadcast during the game on ESPN. Mitchell is in sweats on the sideline after walking out to the field in pads during pregame warmups.

FSU gets on the board first with a touchdown pass - 11:01, Q1

After Louisville went three and out in its opening drive, Florida State marched down the field for a drive that consisted of five plays for 61 yards. The drive was topped off with a 2-yard pass from Jordan Travis to Preston Daniel.

Florida State 7, Louisville 0

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How to watch Louisville football vs Florida state on TV, livestream

Sep 25, 2021; Tallahassee, Florida, USA; Louisville Cardinals wide receiver Braden Smith (4) runs with the ball during the first quarter against the Florida State Seminoles at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-USA TODAY Sports
Sep 25, 2021; Tallahassee, Florida, USA; Louisville Cardinals wide receiver Braden Smith (4) runs with the ball during the first quarter against the Florida State Seminoles at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-USA TODAY Sports

Game time: 7:30 p.m. Friday, Sept. 16

Location: Cardinal Stadium (Louisville)

TV: ESPN

Online livestream: ESPN.com/watch

Terrestrial radio broadcast: 93.9-FM/970-AM

Online radio broadcast: GoCards.com

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Sep 25, 2021; Tallahassee, Florida, USA; Louisville Cardinals defensive back Kei'Trel Clark (13) catches the game ending interception to win the game against the Florida State Seminoles at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-USA TODAY Sports
Sep 25, 2021; Tallahassee, Florida, USA; Louisville Cardinals defensive back Kei'Trel Clark (13) catches the game ending interception to win the game against the Florida State Seminoles at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-USA TODAY Sports

As of Tuesday, Sept. 13, Florida State was favored by 2.5 points.

Odds provided by Tipico Sportsbook. Access USA TODAY Sports’ betting odds for a full list.

Listen to the other side:Podcast with former Florida State QB EJ Manuel on Louisville, Jordan Travis and more

Louisville RB Jalen Mitchell ruled out vs Florida State

The Cardinals announced two hours before kickoff backup running back Jalen Mitchell will miss the home opener. Starter Tiyon Evans will still be the main back, but expect Jawhar Jordan and Trevion Cooley to see extra playing time against the Seminoles.

Louisville coach Scott Satterfield hi fives with a fan during the Card March prior to the Governor's Cup game against Kentucky at Cardinal Stadium. Nov 27, 2021
Louisville coach Scott Satterfield hi fives with a fan during the Card March prior to the Governor's Cup game against Kentucky at Cardinal Stadium. Nov 27, 2021

Finding the right balance for Malik Cunningham is key to unlocking Louisville's offense

For one week, Malik Cunningham got away from what has made him so successful.

In Louisville’s season opener, the Cardinals' dual-threat signal caller didn’t run nearly as much as he has in the past and was held to less than 100 yards rushing in the 31-7 loss to Syracuse. Six days later, the Cardinals changed course.

Cunningham let loose. He rushed for 121 rushing yards to go along with 195 passing yards, accounting for 75% of the team’s offensive yards in the 20-14 win over UCF on Friday. The performance was highlighted by his 43-yard touchdown run with 2:46 left in the third quarter that gave Louisville a 17-14 lead and the first since the opening minutes of the Week 2 clash.

Read more on Cunningham here.

Louisville vs Florida State football history

The Seminoles lead the all-time series 16-6. For games between the two teams played in Louisville, FSU holds the advantage at 6-3.

While Florida State has a convincing lead in the series, Louisville is on a two-game win streak.

Reach recruiting and trending sports reporter Brooks Holton at bholton@gannett.com and follow him on Twitter at @brooksHolton.

This article originally appeared on Louisville Courier Journal: Louisville football loses to Florida State: Video highlights, updates