Colorado is home to four of the 50 largest craft breweries in America — including two of the top eight, according to an annual ranking released Wednesday by the Brewers Association— but that number could drop next year after the sale of its largest independent beer maker. The rankings reflect the amount of beer produced in 2019 by beer makers that met the definition of “craft brewer” — making less than 6 million barrels of beer per year and having no more than 25% of the company owned by an alcoholic-beverage producer that is not a craft brewer — for any part of the year. The four breweries that made the list are: New Belgium Brewing Co. of Fort Collins, which ranked again as the No. 4 largest craft brewer in the country and the No. 11 overall brewer; CANarchy of Longmont — the umbrella of breweries owned by Oskar Blues Brewery that includes Cigar City Brewing of Florida, Perrin Brewing of Michigan and more — which ranked again as the No. 8 craft brewery in the county and 17th-largest overall brewer; Odell Brewing Co. of Fort Collins, which ranked as the No. 19 craft brewer and No. 29 overall brewer — up from No. 23 and No. 33 last year, respectively; and Left Hand Brewing Co. of Longmont, which rose to No. 48 on the craft-brewery list from the No. 50 position last year.