Medtronic CoreValve safer than surgery in bypass patients: study

(Reuters) - Medtronic's CoreValve non-invasive aortic valve replacement system led to significantly fewer deaths than open heart surgery after one year in patients who had previously undergone coronary bypass procedures, according to data from a clinical trial.

One year after a diseased valve was replaced using the CoreValve transcatheter aortic valve replacement (TAVR) system, 11.4 percent of high-risk patients had died or suffered a major stroke versus 21.8 percent among those who had the valve replaced surgically.

There was no significant difference in major strokes alone, so most of the benefit seen in the combined data point came from a reduction in all cause mortality, researchers found.

The data came from a sub-analysis of a larger trial of high risk heart patients, and looked only at the 226 who had previously undergone coronary artery bypass grafting surgery, known as CABG.

"The CoreValve System demonstrated important clinical advantages, including faster recovery compared to surgical valve replacement, offering heart teams an alternative to open heart surgery for this patient population," said Dr. John Conte, a professor of surgery at The Johns Hopkins Hospital, who presented the data at the Society of Thoracic Surgeons meeting in San Diego, in a statement.

The analysis also showed significantly reduced complications for TAVR patients after one year, including lower rates of acute kidney injury (5.3 percent vs 16.3 percent) and life threatening or disabling bleeding (14.0 percent vs. 43.5 percent).

TAVR systems are increasingly being used as an alternative to chest-cracking open heart surgery for patients with aortic stenosis. Using a catheter, the valve is threaded through an artery and into place in the heart.

CoreValve competes with the Sapien TAVR system from Edwards Lifesciences Corp. They are considered important growth drivers for the companies.

The TAVR systems are currently approved for use in patients deemed too frail to undergo surgery or those considered to be at high risk. Both companies are testing their systems in moderate risk patients with the aim toward gaining approval to treat a larger portion of the population.

(Reporting by Bill Berkrot; editing by Gunna Dickson)

  • Fact, along with Trump, is on trial in the Senate
    Yahoo News

    Fact, along with Trump, is on trial in the Senate

    WASHINGTON — “The truth is there,” Rep. Val Demings, D-Fla., said at the opening of the Senate impeachment trial of President Trump, a statement repeated and paraphrased countless times by the seven House impeachment managers, who have treated the case against Trump as self-evidently true based on the facts they have gathered. Now they just have to convince Republicans.

  • China Puts 13 Cities on Lockdown as Coronavirus Death Toll Climbs
    Time

    China Puts 13 Cities on Lockdown as Coronavirus Death Toll Climbs

    China broadened its lockdown to include at least 13 cities Friday as it strives to contain a deadly virus outbreak the World Health Organization has termed a domestic health emergency. The respiratory virus has claimed 26 lives and infected at least 830 people in China since it was first detected at a seafood market in Wuhan last month, according to figures provided by the National Health Commission Friday morning. While cases of the new coronavirus have been detected around the world, from Thailand and South Korea to the United States, WHO said the situation does not yet constitute a global health emergency.

  • Bodies of U.S. firefighters retrieved from Australian air crash site
    Reuters

    Bodies of U.S. firefighters retrieved from Australian air crash site

    The bodies of three U.S. firefighters who died in a plane crash earlier this week in Australia's remote bushland while battling a fierce wildfire have been recovered, the police said on Saturday as investigators started probe into the accident. A spokeswoman for Australia's New South Wales state police confirmed the recovery to Reuters in an e-mail. Coulson Aviation, the private Canadian firm that employed the trio, named them as U.S. military veterans Captain Ian H. McBeth, 44, of Great Falls, Montana, First Officer Paul Clyde Hudson, 42, of Buckeye, Arizona, and Flight Engineer Rick DeMorgan Jr., 43, of Navarre, Florida.

  • Face masks aren't a very effective way to prevent the spread of coronavirus, experts say, despite spiking sales
    Business Insider

    Face masks aren't a very effective way to prevent the spread of coronavirus, experts say, despite spiking sales

    AP Photo/Kin Cheung Of the many preventative measures you can take to protect yourself from the growing Wuhan coronavirus outbreak, wearing a face mask is one of the most visible. But health experts aren't convinced it'll help much. "There's little harm in it," Eric Toner, a scientist at Johns Hopkins Center for Health Security, said of donning a mask.

  • Bloomberg

    Bulgaria Takes Harder Line on Russia Before U.S. Energy Talks

    Bulgaria said it may expel two Russian diplomats it accuses of espionage, demonstrating an unusually tough stance toward the Kremlin in the run-up to talks with the U.S. over energy and security. A European Union and NATO member, the Balkan country is trying to balance the priorities of its Western allies with religious, historical and cultural ties to neighboring Russia, which is also its main energy supplier. The pair -- a first secretary in the Russian embassy's consular department in Sofia and a diplomat in Russia's commercial representation office -- will “most likely” be declared persona non grata, Foreign Minister Ekaterina Zaharieva told reporters.

  • Damaged By Drone Strike: Suleimani's Sainthood Is Now Being Questioned
    The National Interest

    Damaged By Drone Strike: Suleimani's Sainthood Is Now Being Questioned

    In the wake of Washington's assassination of former Quds Force commander Maj. Gen. Qassim Suleimani, Arab Shi'a desires and interests across the Middle East are under a microscope. Have they shifted their protest slogans from opposing Iran to denouncing the United States? Americans should not assume that wide-angle television images of Shi'a protests in Iran calling for the downfall of the Great Satan reflect Shi'a sentiment across Arab societies.

  • Associated Press

    Social worker charged with coercing client into prostitution

    A former child services caseworker has been charged with human trafficking, accused of recruiting a mother who was her client into prostitution in exchange for a favorable custody recommendation, authorities said. Candace Talley, 27, of Winslow, New Jersey, was working for the Division of Children and Youth Services in Delaware County, Pennsylvania, when she coerced the mother, whose children were in foster care and whose case Talley was managing, into working as a prostitute, the Delaware County District Attorney's office announced Thursday. Talley drove the woman to and from jobs and took more than 25% of the money that was made, authorities said.

  • Chinese Uighurs in Saudi face impossible choice
    AFP

    Chinese Uighurs in Saudi face impossible choice

    His eyes brimming with tears, a Uighur student in Saudi Arabia holds out his Chinese passport -- long past its expiry date and condemning him to an uncertain fate as the kingdom grows closer to Beijing. The Chinese mission in Saudi Arabia stopped renewing passports for the ethnic Muslim minority more than two years ago, in what campaigners call a pressure tactic exercised in many countries to force the Uighur diaspora to return home. Half a dozen Uighur families in Saudi Arabia who showed AFP their passports -- a few already expired and some approaching the date -- said they dread going back to China, where over a million Uighurs are believed to be held in internment camps.

  • Millions of locusts are swarming in Kenya. These striking photos show just how bad the outbreak is
    USA TODAY

    Millions of locusts are swarming in Kenya. These striking photos show just how bad the outbreak is

    It's the worst locust outbreak to hit Kenya in 70 years. Hundreds of millions of the small bugs are swarming in from neighboring Somalia and Ethiopia with unprecedented size and destructive potential, according to the United Nations' Food and Agriculture Organization. The Desert Locust, the most devastating of all locust species, is eating up crops in areas already susceptible to food and water shortages.

  • Schiff lobbies Chief Justice Roberts to rule on questions of executive privilege
    Yahoo News

    Schiff lobbies Chief Justice Roberts to rule on questions of executive privilege

    Rep. Adam Schiff, the lead House prosecutor, called on Chief Justice John Roberts to expedite rulings on any disputes between Congress and President Trump over witness testimony and documents, if the Senate votes to allow them. “We have a very capable justice sitting in that Senate chamber empowered by the Senate rules to decide issues of evidence and privilege,” Schiff, the Democratic congressman from California leading the case for impeachment, told reporters prior to the last day of opening arguments for the House impeachment managers. Republicans have said over the past day or so that one reason to vote against subpoenas for documents and witnesses in the trial is that it would drag out the process too long, because Trump would claim executive privilege and the matter would get bogged down in the courts.

  • 'Kids are taking the streets': climate activists plan avalanche of events as 2020 election looms
    The Guardian

    'Kids are taking the streets': climate activists plan avalanche of events as 2020 election looms

    Organizers in the youth climate movement plan an avalanche of activities beginning next week, determined to make the future of the climate the major issue of the 2020 election. Capitalizing on turnout in the September climate strikes, when 6 million people worldwide turned out to demand urgent action to address the escalating ecological emergency, young US organizers are making the leap from mobilization to demands. “The headline message of the strikes in 2020 is: the kids are taking to the streets to strike for climate and they're asking you to vote,” said Katie Eder, the executive director of Future Coalition, a communications and training hub for youth climate groups.

  • Philippine President Duterte threatens to end military deal with U.S.
    Yahoo News Video

    Philippine President Duterte threatens to end military deal with U.S.

    Philippine President Rodrigo Duterte warned the United States on Thursday he would repeal an agreement on deployment of troops and equipment for exercises if Washington did not reinstate the visa of a political ally.

  • A 36-Year-Old Man Is the Youngest Fatality of the Wuhan Coronavirus Outbreak So Far
    Time

    A 36-Year-Old Man Is the Youngest Fatality of the Wuhan Coronavirus Outbreak So Far

    A 36-year-old man in the central Chinese city of Wuhan has become one of the latest—and youngest—victim of the new coronavirus outbreak, local health authorities announced Friday, raising concerns about who can be most affected by the virus. “This 36-year old is an enigma,” said David Heymann, a professor of Infectious Disease Epidemiology at the London School of Hygiene. The man was admitted to a hospital on Jan. 9 after experiencing a high fever for three days, according to the health commission of Hubei province, where Wuhan is located.

  • 2 elephants escaped a circus in Russia and rolled around in the snow before being recaptured
    INSIDER

    2 elephants escaped a circus in Russia and rolled around in the snow before being recaptured

    Reuters/YVES HERMAN Two circus elephants in Russia made a run for it on Thursday. The circus troupe was in the process of loading the animals into a truck when they walked away. The female elephant, Karla, rolled around in the snow in the city of Yekaterinburg.

  • China is Expanding into the Indian Ocean—Here Are Five Things the Indian Navy Can Do About It
    The National Interest

    China is Expanding into the Indian Ocean—Here Are Five Things the Indian Navy Can Do About It

    For decades, the Indian Navy has been the dominant regional power in the Indian Ocean, and has even boasted a carrier aviation capability that was nearly unique in Asia. But as outlined in a report by the Center for New American Security (CNAS), the growth of Chinese military power in the last two decades has dramatically eclipsed India's own attempts to modernize and expand its forces—particularly in the maritime domain. This is problematic due to New Delhi's tense relations with Beijing since a 1962 border war.

  • Someone paid protesters to show up at the Huawei CFO's extradition hearing and pretend they support her
    Business Insider

    Someone paid protesters to show up at the Huawei CFO's extradition hearing and pretend they support her

    CBC/Twitter Two women say they were duped into protesting in favor of Huawei CFO Meng Wanzhou at an extradition hearing in Vancouver, Canada. They said they were offered between 100 and 150 Canadian dollars to show up and hold signs, along with around 20 others. Both said they didn't realize what they were being asked to do, and regret it.

  • Wax On, Wane Off: A Guide to All the Lunar Phases
    Popular Mechanics

    Wax On, Wane Off: A Guide to All the Lunar Phases

    Your guide to the moon—and its many phases. From Popular Mechanics

  • Mexico seeks US extradition of drug lord's son for reporter murder
    AFP

    Mexico seeks US extradition of drug lord's son for reporter murder

    Mexico is seeking the extradition from the United States of the son of a Sinaloa cartel drug lord over the 2017 murder of acclaimed journalist Javier Valdez, the attorney general's office said Thursday. Damaso Lopez Serrano, the son of former top "El Chapo" lieutenant Damaso Lopez Nunez "El Licenciado", is accused of being the mastermind behind the killing of Valdez. An arrest warrant for Lopez Serrano was approved Thursday afternoon after prosecutors interviewed members of the Sinaloa cartel who testified against him, the attorney general's office said in a statement.

  • The best of Adam Schiff from the impeachment trial
    Yahoo News

    The best of Adam Schiff from the impeachment trial

    As House Democrats wrapped up their 24 hours of opening statements in the impeachment trial of President Trump on Friday, one thing members of both parties acknowledged — albeit somewhat grudgingly on the Republican side — was that Rep. Adam Schiff had done about as good a job as he could in arguing the Democrats' case. Schiff, the chairman of the House Intelligence Committee, was the lead impeachment manager for the Democrats, speaking on his feet for hours at a time with fluency, eloquence and command of the facts. “He's well-spoken,” Sen. Lindsay Graham, R-S.C., told reporters on Thursday.

  • Racist threats rattle students, faculty at university
    Associated Press

    Racist threats rattle students, faculty at university

    WINSTON-SALEM, N.C. (AP) — Three months after a set of anonymous, threatening, racist, antisemitic and homophobic emails sent a wave of fear through the sociology department at Wake Forest University, the department chairman says he's still waiting for university leaders to announce a meaningful response. Alarmed by what he deemed white supremacist terrorism, chairman Joseph Soares canceled sociology classes for a week. When they resumed, Wake Forest police officers were stationed outside classrooms and the building itself.

  • Warren responds after angry dad confronts her on student loans
    CBS News

    Warren responds after angry dad confronts her on student loans

    Warren's student loan comments begin at the 6-min. mark in video above After being confronted by a man questioning her student loan forgiveness plan, Democratic presidential candidate Elizabeth Warren dismissed his argument. "We don't build an America by saddling our kids with debt," she said on "CBS This Morning" Friday.

  • This Is What Skiing in Africa Looks Like
    Architectural Digest

    This Is What Skiing in Africa Looks Like

    From the sand dunes of Namibia to South Africa's world-class Tiffindell resort, this is what makes skiing in Africa like no place on the planet Originally Appeared on Architectural Digest

  • Reuters

    In southern Poland, archaeologists discover WW2 plane wreck

    Archaeologists have discovered the wreck of a U.S.-made bomber flown by the Soviet Red Army in World War Two, along with the remains of four crewmen killed when it crashed in southern Poland, private broadcaster TVN reported. Only one man survived when the B-25 Mitchell was shot down by the German air force on Jan. 19, 1945 - a 23-year-old commander who parachuted out and was taken into German captivity. Marta Wrobel in the town of Bierun during the war and told TVN that the blast from the crash had been powerful enough to blow out windows and doors.

  • Why This 1 Missile Problem Is Creating Headaches for Iran's F-14A Tomcats
    The National Interest

    Why This 1 Missile Problem Is Creating Headaches for Iran's F-14A Tomcats

    Key point: Tehran cherishes its American-made F-14 Tomcats, but those fighters are getting very old. Among the many problems facing Iran's F-14s are a lack of missiles. Iran's F-14A Tomcats are an anomaly in the region.

  • Mike Pompeo accused a veteran NPR reporter of 'lying,' being 'unhinged,' and misidentifying Bangladesh for Ukraine on a map
    Business Insider

    Mike Pompeo accused a veteran NPR reporter of 'lying,' being 'unhinged,' and misidentifying Bangladesh for Ukraine on a map

    Reuters In a Saturday statement, Secretary of State Mike Pompeo accused an NPR host and veteran reporter of lying, being an example of the "unhinged" media, and misidentifying Bangladesh as Ukraine on a map. On Friday, NPR's "All Things Considered" host Mary Louise Kelly interviewed Pompeo, and asked him questions about the United States' support for Ukraine and the ouster of former US ambassador to Ukraine Marie Yovanovitch. But Kelly said that after the interview, Pompeo yelled at her for asking the questions on Ukraine in his office, cursed her out, and asked her if she could identify the country of Ukraine on a map.