Which team will get the victory?
The Vikings are a 6.5-point favorite in the game, according to Tipico Sportsbook.
The Vikings are -320 on the money line and the Lions are +250.
The over/under for the game is set at 46.5 points.
Pro Football Network: Vikings 26, Lions 22
Ben Rolfe writes: "Just like that, the Vikings are back in season-saving mode after their loss to the 49ers. A matchup with the Lions should be just what the doctor ordered. However, while the Lions have gone 0-2-1 in the last three weeks, they have been outscored by a total of just 5 points in that time frame. The Lions almost beat the Vikings in Week 5. Divisional games always find a way of being close. The Dalvin Cook injury should not hurt the Vikings too much, but their inability to get out of their own way could. The Vikings should win, but this one could easily be on upset alert late in the fourth quarter."
Sportsnaut: Vikings 42, Lions 21
Matt Johnson writes: "It’s pretty well-known that the Lions have a bottom-five roster, and heck, that’s a generous label. They’d need an unfathomable amount of young players to rise to the occasion in order to have a chance at being competitive even against a Vikings team reeling following an ugly loss to the 49ers. Pick Minnesota going away."
Draft Kings: Take the Lions with the points vs. Vikings in Week 13
Teddy Ricketson writes: "While the Lions haven’t won this season they have covered quite a bit. When these two teams met in Week 5, the Vikings came away with the 19-17 win. The Vikings' offense has been solid with wide receiver Adam Thielen racking up touchdowns, but their defense hasn’t really slowed many offenses. Lions running back D’Andre Swift was banged up on Thanksgiving, but he avoided a major injury. If he and T.J. Hockenson can get back on track in the offense, the Lions should cover here."
Picks and Parlays: Vikings 24, Lions 20
It writes: "Detroit is starting to come around and have shown that they are a team that is improving as the year has went on. A lot of that comes from Goff starting to feel comfortable in Detroit, but still the Lions are struggling and will continue to have problems on the year here as the Vikings have a good defense and a fairly balanced defense."
Sportsnaut: Vikings 30, Lions 17
Vincent Frank writes: "A mediocre defense and one of the worst offenses in the NFL must now faces an underrated Vikings' roster. With D'Andre Swift uncertain to play, the Lions are in real jeopardy of getting blown out at home. At least the fans are used to it."
FiveThirtyEight.com: Vikings have a 77% win probability
The site fives the Lions a 23% win probability in the NFL Week 13 game.
ESPN: Vikings have a 67.8% chance to win
The site's Football Power Index gives the Lions a 31.9% chance to pick up the victory in the Week 13 NFL game.
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This article originally appeared on Arizona Republic: Minnesota Vikings vs. Detroit Lions picks, odds NFL Week 13 game