ZURICH (Reuters) - Novartis said late on Wednesday that a majority of patients given a development drug against non-small cell lung cancer had responded to the treatment, according to study results published in the New England Journal of Medicine. The Basel-based drugmaker's LDK378 has been declared a "breakthrough therapy", a designation created by the U.S. Food and Drug Administration in 2012 to help speed drugs to market that treat serious or life-threatening conditions and are deemed likely to work better than existing treatments. Non-small cell lung cancer is the most common type of lung cancer, and sufferers tend to be non-smokers and younger than other lung cancer patients. Patients survived for an average of seven months after taking LDK378, and 58 percent of those treated with the drug responded, Novartis said. Novartis is currently conducting Phase II and Phase III trials of the treatment. The company, which said in January that it had filed for regulatory approval of the drug, said the data formed the basis for its submission. Novartis, which considers the treatment among the most promising in its pipeline, is facing a "patent cliff" - where a number of best-selling drugs lose market exclusivity. The company is pinning its hopes on what it hopes will be 'blockbuster' treatments for cancer, heart failure and lung disease. (Reporting By Katharina Bart; Editing by Kevin Liffey)
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A 30-year-old with a hoarse voice, back pain, and achy bones visited a walk-in clinic to see a doctor for his symptoms. He found out it was lung cancer.
An otherwise healthy 30-year-old man had a hoarse voice and back pain that wouldn't go away. Doctors found a 4-inch long tumor that spread quickly.
- The Daily Beast
Callaghan O’Hare/ReutersLess than 48 hours after his shocking defeat in North Carolina’s primary election, Rep. Madison Cawthorn took to Instagram to post a defiant, vengeful, and typo-riddled message promising a “Dark MAGA” comeback.After decrying the establishment-driven campaign to unseat him following a long series of scandals, Cawthorn credited those he called his true allies, specifically naming figures like former President Donald Trump, Rep. Marjorie Taylor Greene (R-GA), “the great Char
- Women's Health
Camila Cabello just showed off her strong abs and even a little underboob in an intricate, floral, chain bra top. The singer is all about body positivity!
- The Daily Beast
ReutersRussian soldiers are apparently so sick of Vladimir Putin’s “stupid” war in Ukraine that they are now openly plotting with their own commanders to go AWOL.The Ukrainian Defense Ministry’s Main Intelligence Directorate released a recording on Thursday that is said to show precisely that happening, with a soldier heard in a purportedly intercepted phone call detailing the plan.The soldier, identified by Ukrainian intelligence as one of many men “mobilized” by authorities in occupied Donetsk
The late night host mocked the former president's pull for Dr. Mehmet Oz in the state's Republican primary.
- The Telegraph
The Duke and Duchess of Cambridge attended the charity premiere of the new Tom Cruise movie, Top Gun: Maverick on Thursday night.
- Business Insider
Videos show Russian soldiers leading a group of Ukrainian captives at gunpoint moments before they were executed in Bucha, report says
A New York Times investigation included video that showed Ukrainian captives being marched in a single file while flanked by armed Russian troops.
Nature is made up of some amazing and intriguing creatures. Perhaps one of the most intriguing is the octopus. Some even believe they could be aliens. One mystery that has long evaded scientists is the octopus’s self-destruction after mating. For years, scientists have wondered why octopuses torture themselves after mating. Now, after all this time, … The post Octopuses torture and eat themselves after mating, and scientists finally know why appeared first on BGR.
Deputies: Motorcyclist with concealed carry permit stops knife-wielding driver in road rage incident
Witnesses told deputies that Rivera exited his truck with a knife in his hand and threatened the motorcyclist.
A handful of security guards struggled to catch the interloper, who even attempted to high-five Brewers batter Jace Peterson.
The girls’ track and field team at Albany High School in upstate New York received a suspension after they launched […] The post New York girls track team members suspended after sports bra protest appeared first on TheGrio.
- Country Living
Kelsey Asbille, who stars as Monica Dutton on Yellowstone, walked the 'Top Gun' red carpet with her father.
Two photos that appear to be of Princess Diana and Kate Middleton are prominently featured in the Duke of Cambridge's palace home
- Fox News
Why is Amber Heard looking at jury through testimony during Johnny Depp trial? Legal experts explain
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Trump's endorsement hasn't been enough to put his most controversial or troubled endorsees over the top, as Republican voters look elsewhere.
- Country Living
Country music star shared a stunning photo with her fans on Instagram. Her pink suit has a cutout back and peek-a-boo seat.
- In The Know by Yahoo
Complete stranger shames mom in middle of Walmart for shopping for baby formula: ‘You think my child should starve?’
The mom totally snapped when she heard the stranger's remarks — and now, she's feeling like she went too far.
"I find it odd that when someone decides to get married all the sudden all of the people close to them are responsible for their expenses."View Entire Post ›
The first tweet by @FireBoebert says, "Hi @RepBoebert - Ask @RepCawthorn about us. We look forwarding to getting to know you."
“The next time you turn on the light, think of the incinerators," Catherine Glenn Foster told Congress while under oath on Wednesday.