Princeton vs. Creighton NCAA picks, predictions, odds: Who wins March Madness game?

No. 15 seed Princeton and No. 6 seed Creighton face off on Friday in an NCAA Tournament Sweet 16 game.

The regional semifinal game is scheduled for approximately 6 p.m. MST and can be seen on TBS.

Who will win the game?

Check out these picks and predictions for the contest.

Creighton is a 9.5-point favorite in the game, according to Tipico Sportsbook.

The Bluejays are -525 on the moneyline. The Tigers are +390.

The over/under for the game is set at 139.5 points.

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OddsChecker: Take Princeton with the points vs. Creighton

It writes: "Yale is the only team that was able to beat Princeton by double digits this year, and did so twice. They did so by shooting lights out from three, 53.8%, and getting to the line, 47 free throws. Creighton is 99th in 3 point percentage and 259th in free throw attempts per game. Not exactly the tools to dominate Princeton. So, while this feels like the end of the road for Princeton, it would certainly be a shock to see them dominated."

March Madness Sweet 16 game picks, odds: Michigan State vs. Kansas State | Arkansas vs. UConn | Florida Atlantic vs. Tennessee | Gonzaga vs. UCLA | San Diego State vs. Alabama | Miami vs. Houston | Princeton vs. Creighton | Xavier vs. Texas

Bleacher Nation: Creighton 78, Princeton 66

Andy Molitor writes: "When it has played as at least 10-point favorites this season, Creighton is 5-7 against the spread. When it has played as at least a 10-point underdog this season, Princeton is 1-0 against the spread. The two teams average a combined 12.2 more points per game (152.2) than this matchup’s over/under of 140 points."

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Dimers: Creighton 74, Princeton 65

It writes: :"Dimers.com's predicted final score for Princeton vs. Creighton at KFC Yum! Center on Friday has Creighton winning 74-65."

NCAA Tournament odds: 2023 March Madness point spreads, money lines, over/unders for games

Sports Chat Place: Go with Princeton with the points vs. Creighton

Randy Chambers writes: "The Creighton Bluejays are the better, more talented team and should be favored and should advance. Creighton has great balance, experience, and was considered a title contender before the season started. This run should surprise nobody. With that said, Princeton continues to win and cover numbers despite not getting much national attention. In fact, since January 7, Princeton is 6-1 SU and ATS in the underdog role. That’s putting money in your pockets, folks. I’ll ride the trend of the team that loves being underdogs. Give me Princeton."

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ESPN: Creighton 76, Princeton 65

Jeff Borzello writes: "Creighton's season has come full circle. The Bluejays entered it as a top-10 team picked to win the Big East. Then they lost six in a row in November and December and sat at 9-8 in mid-January. Suddenly, they're a win over 15-seed Princeton away from playing for a trip to the Final Four. And I think they'll get that chance. Greg McDermott's team has five legitimate offensive weapons who can all go for 25 or 30 points, and it had the best defense in the Big East. Princeton has looked incredible for two games, but Creighton will prove too tough."

How to watch NCAA Tournament regional semifinal games: Michigan State vs. Kansas State | Arkansas vs. UConn | Florida Atlantic vs. Tennessee | Gonzaga vs. UCLA | San Diego State vs. Alabama | Miami vs. Houston | Princeton vs. Creighton | Xavier vs. Texas

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Princeton vs. Creighton NCAA March Madness picks, predictions, odds