This rabies strain was never west of the Appalachians, until a stray kitten showed up in Nebraska

A stray kitten is partly responsible for a multi-agency effort to extinguish a strain of rabies, commonly found in raccoons, that had never been seen west of the Appalachian Mountains.

It all started when the Wahl family brought a black-and-white stray kitten a little over a month-old back to their Omaha home after a friend found it meowing in her driveway, according to reporting by The Washington Post. 

The tiny feline, named Stanley, was taken to a local veterinarian not long after the Wahls brought him home for what appeared to be a bad reaction to ringworm medication, shaking and flailing his legs after each dose.

He had also stopped eating and developed seizures, appearing to get sicker as time went on.

Sharon Mix, a veterinarian at VCA Animal Medical Center of Omaha noted that the kitten’s unusual physical symptoms could be the result of nearly two dozen possible causes.

Rabies was never on the list, because it's rare to see it in domesticated animals, Mix told The Post. Stanley died a couple of days later, exhibiting neurological symptoms worth testing.

The kitten tested positive for raccoon rabies on Sept. 28, prompting the creation a week later of a joint task force made up of Douglas County, Nebraska, public health officials, the USDA’s Wildlife Services and the rabies epidemiology team at the Centers for Disease Control and Prevention assigned to vaccinate raccoons in the area against possible infection.

The CDC was able to confirm the result of Stanley’s test on Oct. 6, elevating the response quickly to prevent the virus from becoming established in the area, CDC epidemic intelligence service officer Dr. Sydney Stein told the Omaha World-Herald. 

If left untreated, the disease could spread outside Omaha and into surrounding areas by way of the raccoon population. The strain could make its way toward South Dakota, Minnesota, Iowa, Missouri and Kansas, endangering an estimated 7 million people, a CDC official told The Post.

“My first thought was it has to be a mistake,” said Ryan Wallace, who heads the rabies epidemiology team at the CDC.

Here’s what we know.

What happened to the people who came in contact with Stanley?

The 10 people who who were around Stanley, including Rich and Madeline Wahl, Mix, veterinary staff and the family who initially found the kitten, have received four doses of the rabies vaccine and one dose of human rabies immune globulin to neutralize the virus, according to the CDC. 

Everyone involved in Stanley’s care began treatment and are doing well, Omaha World-Herald reported. 

What has been done to mitigate the raccoon rabies strain?

In the days and months after Stanley’s death, surveillance and vaccination efforts have been led by more than a dozen USDA wildlife biologists and CDC disease detectives.

USDA wildlife biologists have gone to work on luring raccoons into traps with anise oil and marshmallows to vaccinate animals in the hopes of preventing the spread. CDC scientists have set up labs in trailers to test roadkill in surrounding areas, The Post reported.

More than 750 raccoons, 41 skunks, four feral cats and one red fox have been vaccinated around the area where the kitten was found, The Post reported. Of the more than 250 dead animals collected by the CDC for testing, none has tested positive for rabies.

Multiple agencies, including the USDA, have placed 18,000 packets containing the oral rabies vaccine around storm drains, trees and bushes and in the woods near walking paths.

The packets, similar to packaged condiments, come coated with wax and fishmeal to attract the raccoons.

The efforts made to mitigate the possible spread were intended to create a “wall of immunity” against the variant among raccoon populations in the area, according to the Omaha World-Herald. 

“As they chew on it, they are bathing their mouth and tonsils with the vaccine, and that starts the immune reaction,” Richard Chipman, coordinator of the national rabies program at the U.S. Department of Agriculture, told The Post.

The practice of dropping packets with rabies vaccines is one federal officials have used to extinguish the threat of rabies since 1997. About 10 million doses of the vaccine are dropped over 16 states every year, from Maine to Texas.

There has been a 50% reduction in the number of rabid raccoons reported across the country because of multi-agency efforts to manage the number of rabies cases.

Normally, the vaccines reach 30% to 40% of an area’s raccoon population, but Omaha has a large raccoon population. As many as 104 raccoons per square mile in certain parts of the city have been reported, Wallace told The Post.

What happens next?

Officials won’t find out until February whether the mitigation efforts over the past couple of months have worked.

Any other animals that might have come in close contact with Stanley might not show symptoms until December, because the incubation period for the virus ranges between one week to three months, The Post reported.

Scientists will continue to test dead animals for the virus because it's a foolproof way to know which animals have gotten the virus. The number of tests depends on the availability of animal carcasses turned over to the CDC.

If the virus has spread prominently through the Omaha area, officials will see 1% to 5% of dead animals testing positive.

“If we can test (a total) of 500 animals over the next few months through this surveillance program and all are negative, then there is likely no spread in local wildlife,” Wallace told The Post.

Where or how Stanley became infected is still unknown, but officials have hypothesized that a pregnant cat or its kitten were bitten and infected by a raccoon in the southeastern United States, where the virus most closely resembles the genetic fingerprint found in Stanley, according to The Post.

The pair, or Stanley, made their way to Omaha over time.

“Had my husband not resuscitated him, we likely would have buried the kitten in our yard and not known about him being rabies positive,” Stanley’s former owner Madeline Wahl told The Post.

Contributing: Lena H. Sun, Washington Post; Julie Anderson, Omaha World-Herald

This article originally appeared on USA TODAY: Why a kitten with rabies in Nebraska led to a regional health scare