Laura Muldoon tweeted a photograph of a group of men who she said called her a “miserable b****h,” “d***” and “lesbo” on a Ryanair flight from London Stansted to Seville, Spain.
“Oh yeah, flight crew did nothing,” she added.
After sending the tweet, she was sent several messages of support and the airline told her to contact them so staff could investigate the alleged incident.
If the police pursue the incident it will be treated as a hate crime and should the accused be convicted, they are likely to be fined and ordered to carry out unpaid work.
The abuse comes weeks after a high-profile attack on two lesbian women in London.
Melania Geymonat, 28, was traveling on a London bus with her girlfriend when they were repeatedly told to kiss by a group of men. When they refused they were assaulted.
The women appeared bloodied and distressed in a photograph which Geymonat shared on Facebook following the horrendous incident.