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San Diego State vs. Alabama NCAA picks, predictions, odds: Who wins March Madness game?

No. 5 seed San Diego State and No. 1 seed Alabama face off on Friday in an NCAA Tournament Sweet 16 game.

The regional semifinal game is scheduled for 3:30 p.m. MST and can be seen on TBS.

Who will win the game?

Check out these picks and predictions for the contest.

Alabama is a 7.5-point favorite in the game, according to Tipico Sportsbook.

The Crimson Tide are -330 on the moneyline. The Aztecs are +260.

The over/under for the game is set at 137.5 points.

More:March Madness Sweet 16 game picks, predictions: More upsets in NCAA regional semifinals

OddsChecker: Take Alabama to cover against San Diego State

It writes: "A tight spread makes sense here as San Diego State is one of the few teams left in the tournament who has a chance to stop the Alabama offensive machine. The issue though is they don’t have the size and physicality to go shot for shot with them even if they do slow them down. It’s why they lost to both Arizona and Arkansas earlier in the season. That gives Alabama the clear edge in this one."

March Madness Sweet 16 game picks, odds: Michigan State vs. Kansas State | Arkansas vs. UConn | Florida Atlantic vs. Tennessee | Gonzaga vs. UCLA | San Diego State vs. Alabama | Miami vs. Houston | Princeton vs. Creighton | Xavier vs. Texas

College Football News: Alabama 72, San Diego State 64

Pete Fiutak writes: "Alabama will have the offensive burst in the second half that San Diego State can't create, and then the amazing D will shut the game down over the final five minutes to move on."

NCAA Tournament schedule, TV: March Madness game times, channels, announcers, how to watch

FanDuel: Alabama 70, San Diego State 64

Larry Rupp writes: "While this may be a tough matchup for Alabama, head coach Nate Oats' team is a No. 1 seed for a reason. The Crimson Tide are averaging 79.0 points over its last five games and ranks 35th in offensive efficiency this season. They have more than enough depth to pull out a close win in the end."

NCAA Tournament odds: 2023 March Madness point spreads, money lines, over/unders for games

March Madness: Will San Diego State beat Alabama in the Sweet 16 of the NCAA Tournament on Friday?
March Madness: Will San Diego State beat Alabama in the Sweet 16 of the NCAA Tournament on Friday?

Dimers: Alabama 70, San Diego State 64

It writes: "Dimers.com's predicted final score for San Diego State vs. Alabama at KFC Yum! Center this Friday has Alabama winning 70-64."

March Madness odds: Houston, Alabama, 2023 men's NCAA Tournament favorites

Bleacher Nation: Alabama 74, San Diego State 69

Andy Molitor writes: "In games this season it was favored by 7 points or more, Alabama has a 12-10 record against the spread.  These two teams average a combined 154.2 points per game, 19.2 more points than the over/under of 135 set for this matchup. Alabama and San Diego State have seen their opponents average a combined 3.7 fewer points per game than the over/under of 135 set for this outing."

How to watch NCAA Tournament regional semifinal games: Michigan State vs. Kansas State | Arkansas vs. UConn | Florida Atlantic vs. Tennessee | Gonzaga vs. UCLA | San Diego State vs. Alabama | Miami vs. Houston | Princeton vs. Creighton | Xavier vs. Texas

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: San Diego State vs. Alabama NCAA March Madness game predictions, odds