Which team will get the victory?
Check out these NFL Week 5 picks and predictions for the game, which can be seen at 10 a.m. MST on Fox.
The Saints are a 5.5-point favorite in the game.
The Arizona Republic: Saints 24, Seahawks 17
Jeremy Cluff writes: "The Saints have had some tough luck and injuries this season. We predict that they will bounce back against the Seahawks at home."
Bookies.com: Take the under in Seahawks vs. Saints game
Bill Speros writes: "The Seahawks offense was money in Week 4. Rashaad Penny ran for 151 yards and scored a pair of touchdowns as Seattle scored 48 points against Detroit. Geno Smith added 320 yards through the air and a pair of TD tosses. The Saints return from a tough loss in London. The total on this game soared from 41 points to 47.5 points after Sunday's results. This has the potential to be a low-scoring, ugly slog. Take the under for your NFL Week 5 best bets."
ESPN: Saints have a 73.4% win probability
The site's Football Power Index gives the Seahawks a 26.4% chance to win the NFL Week 5 game.
Draft Kings: Go with the Seahawks with the points vs. Saints
It writes: "Despite the many questions about the Seahawks heading into this season, Smith looks to have a comfortable command of the offense as Seattle has largely remained competitive through the quarter-mark of the season. Meanwhile, New Orleans’ offense has been plagued with the injury-bug after the health status of Jameis Winston, Michael Thomas, and Alvin Kamara seems to be up in the air. Given their performance through the first four weeks, I like the Seahawks to keep this game competitive in Week 5."
NFL week 5 schedule: How to watch Week 5 NFL games
Sports Betting Dime: Saints 18.1, Seahawks 12.8
The site's formula predicts that the Saints will win a low-scoring game on Sunday.
Fan Duel: Bet the Seahawks with the points vs. Saints
Larry Rupp writes: "This Saints could pull away in the second half of this battle, according to the opening betting lines. ESPN's FPI also doesn't see the game being too close, but I'm siding with the Seahawks here. The Saints were without quarterback Jameis Winston, running back Alvin Kamara and wide receiver Michael Thomas in Week 4. The absence of any of those guys in Week 5 could cause some issues on offense. Quarterback Geno Smith is avoiding risks and making plays."
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This article originally appeared on Arizona Republic: Seattle Seahawks vs. New Orleans Saints picks, predictions NFL Week 5