Ryan Tannehill fired a decisive 23-yard touchdown pass to Adam Humphries with 23 seconds remaining Sunday and the Tennessee Titans stunned the Kansas City Chiefs, 35-32, in Nashville, Tenn.
Harrison Butker, who made a field goal as time expired to enable the Chiefs to beat Minnesota last week, had a 52-yard attempt blocked at the buzzer.
The Chiefs (6-4) lined up for a field goal after going three-and-out inside the final 2 minutes but holder Dustin Colquitt could not handle the snap and was flagged for intentional grounding on a desperation pass.
Tannehill and the Titans (5-5) took over and covered 61 yards in four plays to spoil the return of Chiefs quarterback Patrick Mahomes, who missed the two previous games with a dislocated knee.
Mahomes, playing with a brace on his right knee, passed for 446 yards, going 36 of 50, with three touchdowns.
Derrick Henry countered with 188 yards rushing and two touchdowns for the Titans, who endured six lead changes. Henry scored on a 68-yard burst in the third quarter, then added a 1-yard plunge to cut the lead to two points with 6:26 remaining.
Tennessee then managed to limit the Chiefs to a field goal, the fourth of the game for Butker, though the boot gave the Chiefs a 32-27 lead with 3:19 left. Kansas City, however, could not run out the clock and Tannehill, who passed for 181 yards and two touchdowns, rallied Tennessee.
Tennessee used a 53-yard touchdown return off a fumble recovery by linebacker Rashaan Evans to gain a 13-10 lead with 6:14 remaining in the first half.
The score came barely 4 minutes after Tannehill led a four-play scoring drive, including a 9-yard TD pass to Anthony Firkser.
An interception on Mahomes' first attempt was overturned on review. He then completed 6 of 8 passes, including a 3-yard shovel pass to Travis Kelce for a touchdown, on the game's opening drive.
Kansas City then recovered a sack and strip by defensive tackle Chris Jones to set up a 30-yard field goal by Butker for a 10-0 lead.
--Field Level Media