(Reuters) - Canadian drugmaker Tekmira Pharmaceuticals Corp has begun limited manufacturing of a therapeutic targeting the Ebola-Guinea virus. The pharmaceutical company said on Tuesday that the new drug, part of its TKM-Ebola program, would be available by early December but did not specify how many doses it was making. Tekmira was not available for comment on the therapeutic, including whether it was manufacturing a drug or vaccine. Tekmira's investigational new drug application to U.S. regulators for TKM-Ebola remains on partial clinical hold, with the issue expected to be resolved in the quarter. U.S.-listed shares of the company rose as much as 6 percent in trading after the company gave an update on its Ebola program. Tekmira has completed the design of a modified RNAi (ribonucleic acid interference) drug that targets the Ebola-Guinea variant, the virus responsible for the worst outbreak on record that has hit hardest Liberia, Sierra Leone and Guinea. TKM-Ebola, an RNAi therapeutic, works by preventing the virus from replicating. The European Medicines Agency said on Monday it was ready to offer Ebola treatments and vaccines the benefits of "orphan" drug status - including extended market exclusivity - in a bid to encourage their development. Initial clinical trials of Ebola vaccines from GlaxoSmithKline and NewLink Genetics are already under way, the World Health Organization said on Tuesday. Mapp Biopharmaceutical Inc gave its experimental Ebola treatment ZMapp to American medical workers Dr. Kent Brantly and Nancy Writebol, who recovered after contracting Ebola in Liberia, and to at least one Spanish priest, who died. Mapp said it had begun manufacturing the drug using traditional methods, which would allow the company to produce more of the drug so that human testing can be carried out. Three Ebola cases have been diagnosed in the United States: Liberian Thomas Eric Duncan, who died on Oct. 8 at Texas Health Presbyterian Hospital in Dallas, and two nurses who treated him. In September, U.S. and Canadian regulators authorized the use of Tekmira's TKM-Ebola in patients who have confirmed or suspected infections from the deadly virus. (Reporting by Tanvi Mehta in Bangalore; Editing by Lisa Shumaker)
Our goal is to create a safe and engaging place for users to connect over interests and passions. In order to improve our community experience, we are temporarily suspending article commenting
- NBC Sports Boston
What can Celtics fans expect from new head coach Ime Udoka? This 2015 quote from Spurs coach Gregg Popovich should generate plenty of excitement.
- Yahoo Sports
Gordon has worked for Fox ever since he retired from the Cup Series. Now he'll be the No. 2 man at Hendrick behind Rick Hendrick.
A month out from the Tokyo Olympics, the US men's basketball roster is taking shape, and it once again looks like a juggernaut.
- The Daily Beast
Screenshot/YouTubeA massive country music festival in Kentucky this past weekend started off on rocky footing: Police found meth, marijuana, and an open bottle of alcohol in the first vehicle they stopped at a traffic checkpoint. One of the people in the car had two active warrants out for their arrest.“We were like, ‘Well, this doesn’t bode well for the weekend,’” Edmonson County Sheriff Shane Doyle told the Lexington Herald-Leader.By the end of the five-day bash, dubbed the “Redneck Rave,” one
The Suns took advantage of a little-known rule their star center wasn't even aware of to execute the game-winning 'Valley Oop'
Deandre Ayton's game-winning dunk would be an offensive goaltend on any other play, but not off an inbounds play.
- Yahoo Canada Style
'It's a whole different face': Kylie Jenner fans react after viral TikTok compares old photos of the star
"She's literally not the same person."
Prince William and Kate Middleton reportedly refused to speak to Prince Harry after Prince Philip's funeral in case the conversation was leaked
The couple thought Meghan Markle might leak their conversation to Oprah Winfrey, the royal historian Robert Lacey said in an updated book.
- Business Insider
Trump's obsessive rants about the 2020 election have driven away his daughter Ivanka and son-in-law Jared Kushner, report says
Ivanka and Kushner have conspicuously stepped back from Trump's inner circle partly over Trump's obsession on the past, CNN reports.
- Golf Channel
Brooks Koepka said the origins of the Brooks-Bryson beef started when DeChambeau didn't stay true to his word.
The former president claims he could be back in power soon.
- NBC Sports BayArea
With the lottery results now official, let's examine five players the Warriors could target on July 29.
This video will live rent-free in my mind henceforth.
- Kansas City Star
Chances are, you’ve never seen something like this at soccer game.
- NBC Sports BayArea
There are a lot of players the Warriors could select with their No. 7 and No. 14 picks on draft night. But who are some guys Golden State should stay away from?
On July 1 — what would have been Princess Diana’s 60th birthday — a new statue of the late princess will be revealed at Kensington Palace, with her sons Prince William and Prince Harry there to honor the moment together despite their ongoing rift, widened by Harry’s confessions about the royal family on his TV […]
- Warriors Wire
At the 2021 NBA draft lottery, the Golden State Warriors officially landed the No. 7 and No. 14 overall picks on the draft board.
- NBC News
More Black people died in traffic deaths in 2020 than any other racial group even though Americans drove less in the pandemic. Experts say this is not new.
An Insider reporter thought Martha Stewart's recipes were the easiest meals she's ever made in a slow cooker.
- Women's Health
Is there anything she can't do?
- Miami Herald
Immigration authorities in the United States have rescinded one of the policies implemented by the Trump administration that had one of the most profound negative impacts on legal immigrants with pending or upcoming applications.