Tennessee Titans vs. New England Patriots picks, predictions: Who wins NFL Week 12 game?

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The Tennessee Titans and New England Patriots play Sunday in a Week 12 NFL game.

Which team will get the victory?

Check out these NFL Week 12 picks and predictions for the game, which can be seen at 11 a.m. MST time on CBS.

The Patriots are a 5.5-point favorite in the game.

More NFL Week 12 picks, predictions:

More: Tennessee Titans vs. New England Patriots NFL Week 12 odds, how to watch, TV information

Pro Football Network: Patriots 27, Titans 23

Ben Rolfe writes: "My my, how things change in the NFL in a couple of weeks. The Titans just lost their second game this season to one of the worst teams in the AFC, while the Patriots look like a Brady-era juggernaut. The Titans’ offense looked out of sync, and now they have to face a Patriots team that has allowed just 13 points in the last three weeks. Meanwhile, New England’s offense is doing what it needs to and allowing their defense to win games. Mike Vrabel knows how to play this Patriots offense, but it is hard to imagine Bill Belichick letting a former player beat him three times in a row."

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Sportsnaut: Patriots 24, Titans 17

Matt Johnson writes: "Bill Belichick is better than anyone at neutralizing his opponent’s best player. With Henry out for the year and Julio Jones on IR, the game plan is easy. New England will contain A.J. Brown, not worry about the Titans’ rushing attack and pressure Ryan Tannehill into terrible throws."

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Draft Kings: Patriots will cover in Week 12 game vs. Titans

Teddy Ricketson writes: "Let’s get wild and just predict as much chaos as possible for this NFL season. Star wide receiver for the Titans, AJ Brown, dealt with injuries in the Week 11 game and his status for this one will certainly be a thing to monitor all week. The Titans showed that they can’t do much on offense without his presence and the Patriots defense showed that they can shut down teams that are lacking any sort of star players. Patriots should cover if Brown is less than 100%."

More: NFL Week 12 schedule, television information for all 15 Week 12 NFL games in 2021 season

Fansided: Patriots 21, Titans 17

Peter Panacy writes: "This isn’t a great game to predict a Tennessee road upset. Vrabel hasn’t been able to fully recover from the earlier loss of running back Derrick Henry. And while the Titans still managed some signature wins before falling flat against the Texans, trying to replicate any success against one of the NFL’s best defenses on the road won’t be easy. As long as rookie quarterback Mac Jones protects the ball and doesn’t make mistakes, New England can afford to be methodical on offense and smothering on defense."

NFL Week 12 game odds, television information:

Will Mac Jones and the New England Patriots beat the Tennessee Titans in Week 12 of the NFL season?
Will Mac Jones and the New England Patriots beat the Tennessee Titans in Week 12 of the NFL season?

CBS Sports: Patriots faring well against the spread entering game vs. Titans

Tyler Sullivan writes: "This is arguably the biggest game on the Week 12 slate for what it could mean for the playoff picture in the AFC. After New England's win on Thursday and the Bills' loss to the Colts on Sunday, the Patriots have now leaped into first place in the AFC East and are currently the No. 3 seed in the conference. Meanwhile, the Titans still sit as the No. 1 seed in the conference, despite the upset loss to Houston. If New England can extend its winning streak to six games, however, it would be in a position to move even higher in the playoff bracket. The Patriots are 5-0 ATs over the last five weeks and are 4-0 in their last four games as a favorite. That said, Tennessee is 5-0 ATS in their last five as an underdog, so something will need to give on Sunday in Foxborough."

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Sportsnaut: Patriots 24, Titans 20

It writes: "Bill Belichick is better than anyone at neutralizing his opponent’s best player. With Henry out for the regular season, he can focus his attention squarely on A.J. Brown or Julio Jones."

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FiveThirtyEight.com: Patriots have a 62% win probability

The site gives the Titans a 38% win probability in the NFL Week 12 game.

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ESPN: Patriots have a 67.5% chance to win

The site's Football Power Index gives the Titans a 32.3% chance to pick up the victory in the Week 12 NFL game.

More: NFL Week 12 picks, predictions: Who wins each Week 12 NFL game?

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared on Arizona Republic: Tennessee Titans vs. New England Patriots picks, predictions Week 12