Spurs’ fixture against Burnley was postponed at late notice last weekend after heavy snow left the pitch in an unplayable condition.
Meanwhile, Brentford ended their winless run against Everton on Sunday and can leapfrog Spurs in the table with a victory tonight.
Here is everything you need to know:
When is it and what time is kick-off?
The match will get underway on Thursday 2 December at 7.30pm.
How can I watch it online and on TV?
The match will be broadcast live on Amazon Prime and will be available on TV as well as mobiles and tablets.
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What is the team news?
Cristian Romero, Giovani Lo Celso and Dane Scarlett all remain sidelined for Spurs.
Brentford have a host of injury issues. Joshua Dasilva, David Raya, Kristoffer Ajer and Julian Jeanvier are ruled out, and there are doubts over the fitness of Rico Henry, Christian Norgaard, Sergio Canos and Mathias Jorgensen.
Tottenham: Lloris; Sanchez, Dier, Davies; Emerson, Skipp, Hojbjerg, Reguilon; Lucas, Kane, Son
Brentford: Fernandez; Goode, Pinnock, Jansson; Canos, Norgaard, Onyeka, Janelt, Henry; Toney, Wissa
Tottenham - 8/10
Draw - 29/10
Brentford - 9/2