By Stephanie Nebehay and Tom Miles GENEVA (Reuters) - The World Health Organization (WHO) said on Friday blood-derived products and serum from survivors may be used to treat Ebola virus immediately and two vaccines could be available for health workers by year-end. Existing supplies of all experimental medicines are limited and will not be sufficient for months to come, while the outlook for vaccine supplies looks "slightly better", the WHO said in a statement after two-day talks attended by nearly 200 experts. But good clinical care, rigorous infection prevention and control measures, and the tracing of people who have been exposed remain crucial for ending an epidemic that has killed at least 2,097 in West Africa since March, the U.N. agency said. "There is a real opportunity that blood-derived products can be used now. This can be very effective in terms of treating patients," WHO assistant director-general Marie-Paule Kieny told a news conference in Geneva. "With the negative point that we have so many patients, one positive point is there are also many people now who are convalescent, who survived and are doing well, These people can provide blood, serum to treat," she told a news conference. "What is available will be used in the field to treat real patients as soon as possible." Studies suggest that blood transfusions from Ebola survivors might prevent or treat Ebola virus infection in others, but it is not known whether antibodies in the plasma of survivors are sufficient, according to the United Nations health agency. Two "promising" Ebola vaccines have also been identified after showing promising results in animals, and safety results from human clinical trials may be available from November, paving the way for their use, Kieny said. The two vaccines are made by GlaxoSmithKline Plc and NewLink Genetics , according to WHO documents. "These must be prioritised in terms of clinical development," Kieny said. Clinical trials of the GSK vaccine have begun in the United States, while trials for the NewLink vaccine will start by mid-September in Europe and Africa, she said. Pending initial results on the vaccines' safety, expected in November, they will be given to health care workers in the field as a priority, with their informed consent, she said. "If we have good safety data, if the results are positive, they will start to be used in health care workers in order to protect and also to evaluate if it protects them," Kieny said. "We will have results of safety by November 2014 and after that these vaccines will start to be rolled out starting with health care workers and front line workers in the field." ZMAPP DRUG "ENCOURAGING" ZMapp, made by the U.S.-based Mapp Biopharmaceutical Inc., has been given to seven people infected with Ebola, including two American aid workers and a Briton who all recovered, but it remains unproven and supplies have run out. The U.S. government pledged up to $42.3 million this week to accelerate its testing. "For the time being there's not enough experience to conclude whether this treatment works or not," Kieny said of the antibody drug ZMapp. "There seem to be encouraging signs." "As soon as there are supplies available they will be tried." Dr. Larry Zeitlin, president of the California-based Mapp Biopharmaceutical, told Reuters that Washington's support was vital to conducting early-stage safety studies of the drug as the jury is still out on both its safety and efficacy. "The U.S. support will enable us to figure out what the appropriate dose is and scale up manufacturing. With a drug you have not only to make it, but make it consistently to the same quality. The award given us is for 18 months. We will probably be in human trials beginning in 2015," Zeitlin said in an interview on Friday on the sidelines of the WHO meeting. "We don't have data indicating whether ZMapp is safe in humans, we don't have data that it works in humans. That is the whole point of performing clinical trials," he said. (Reporting by Stephanie Nebehay and Tom Miles; writing by Stephanie Nebehay; editing by Andrew Roche)
- Associated Press
For National Park Service fisheries biologist Jeff Arnold, it was a moment he'd been dreading. Bare-legged in sandals, he was pulling in a net in a shallow backwater of the lower Colorado River last week, when he spotted three young fish that didn't belong there. Minutes later, the park service confirmed their worst fear: smallmouth bass had in fact been found and were likely reproducing in the Colorado River below Glen Canyon Dam.
The Georgia Republican spoke just days after seven people were killed in a mass shooting at a parade in Illinois.
Dad of Highland Park suspect said he sponsored his son's gun permit application because he thought he wanted to go to the shooting range
A gunman opened fire on a Fourth of July parade in Highland Park, Illinois. Seven people were killed. A 21-year-old suspect has appeared in court.
Scheana Shay and Lala Kent celebrated the Fourth of July in style. The Vanderpump Rules cast members enjoyed the holiday in sizzling swimsuits while in San Diego. On July 5, Scheana took to Instagram to show off her and Lala’s festive swimwear. The Scheananigans podcast host was beautiful in a red Tobi bikini. The ribbed crimson two-piece featured cheeky bottoms and a bandeau top with a smoldering cutout that revealed her underboob. She completed her look with a thick black headband and a rainbo
- In The Know by Yahoo
The bed wasn't the only thing they left their mark on.
This Woman Is Calling Out Those Who Think She And Her Husband's Relationship "Doesn't Make Sense" Just Because Their Bodies Are Different
"People's values don't lie in how well their bodies fit into society's trash beauty standards."View Entire Post ›
Kate Middleton and Prince William pulled a very rare move today, being very, very affectionate at the Royal Charity Polo Cup 2022.
- The Daily Beast
Mikhail Svetlov/Getty ImagesRussian officials have begun to issue a series of threats to the United States in an attempt to fend off a war crimes tribunal, with top officials suggesting that Russia could be interested in going after Alaska next, which the United States purchased from Russian in 1867.Russia’s lower house speaker, Vyacheslav Volodin, warned the United States ought to hesitate when seizing or freezing Russian assets abroad, and instead ought to remember that Alaska previously belon
The mother of the suspect in Monday’s deadly mass shooting in Highland Park has been at the center of some police contact for hours on Tuesday, as well as with a SWAT team in the hours after the shooting.
- NBC Sports BayArea
Otto Porter Jr. depicted why he chose to sign with the Toronto Raptors over reuniting with the reigning NBA champion Warriors.
- In The Know by Yahoo
Bridesmaid contemplates dropping out of wedding over bride’s ‘gaslighting’ behavior: ‘Do not go to the wedding’
All she wanted was the answer to a simple question.
- USA TODAY Sports - Golfweek
Justin Leonard dishes on the night Phil Mickelson threw BP at a Double-A game (and bet players they couldn’t homer off him)
"I said, ‘Do you guys want to go watch?’ And Fred (Couples) said, 'I wouldn't miss this for the world.'"
- Fox News
Hollywood producer David Pearce, accused of murdering two women, may have more victims, prosecutors say
A Beverly Hills man has been charged with murder for the deaths of two women and there may be more victims, Los Angeles DA George Gascón said Tuesday at a press conference.
- Fort Worth Star-Telegram
The man had been shooting off fireworks with a friend when one exploded the wrong direction.
- The Daily Beast
Photo Illustration by Elizabeth Brockway/The Daily Beast/GettyRussian forces took a key region in eastern Ukraine over the weekend, thanks in part to Moscow stepping up its coordination and war planning, according to a British intelligence assessment released on Tuesday.This change in Russian forces’ approach to fighting in Eastern Ukraine could be the early signs of a brand new—and worrying—phase in Russia’s devastating war in Ukraine.While Ukrainian officials first denied that they had lost Ly
- The Daily Beast
IKHAIL KLIMENTYEV/Sputnik/AFP via Getty ImagesRussian President Vladimir Putin’s key ally Belarusian leader Alexander Lukashenko has started hinting at what may be next in Russia’s war, and it doesn’t sound pretty.Lukashenko claimed this weekend that he thinks it’s time for Europe to face a “moral cleansing.”“The time has come for the forgetful Europe to give itself a moral cleansing,” Lukashenko said, without going into further detail about what that would entail, according to BelTA.Lukashenko
Kenny's never met a swimsuit she doesn't like.
"Our goal was to create stylish swimsuits that women of all ages can feel confident, secure, and comfortable wearing," she tells InStyle, exclusively.
- The Hill
Sen. Lindsey Graham (R-S.C.) achieved new heights of political celebrity during the Trump years, but now finds himself in the middle of a criminal investigation linked to the battle for Georgia in the 2020 presidential race. A special grand jury in Fulton County has subpoenaed Graham along with other Trump insiders as part of an…
Trump's children were split between denial and rage after he lost the election, says filmmaker with the family around Jan. 6
Alex Holer, who got exclusive access to the Trump family, told Insider they dealt with the election loss in very different ways.