PHILADELPHIA — After sitting out the first game of his NFL career due to a knee injury, Vikings rookie safety Lewis Cine made his NFL debut on Monday night against the Philadelphia Eagles at Lincoln Financial Field.

Cine, a reserve safety who plays on special teams, was Minnesota’s top draft choice last April, going No. 32 in the first round. The Vikings’ second selection in that draft, cornerback Andrew Booth Jr., who went in the second round, was inactive Monday. He was ruled out of the game on Saturday due to a quadriceps injury suffered in a 23-7 win over Green Bay in the opener on Sept. 11.

Also inactive for the Vikings were offensive lineman Chris Reed, running back Ty Chandler, edge rusher Luiji Vilain, tackle Vederian Lowe and defensive lineman Esezi Otomewo. All but Reed, who played at Minnesota State Mankato and is entering his seventh NFL season, are rookies.

Inactive for the Eagles were quarterback Ian Book, safety Reed Blankenship, running back Trey Sermon, guard Josh Sills, tight end Grant Calcaterra and defensive end Janarius Robinson. Robinson was signed last week off Minnesota’s practice squad.

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