The Cowboys are -170 on the moneyline in the game, which will be played at AT%T Stadium in Arlington, Texas.
The Commanders are +145.
The over/under for the game is set at 41.5 points.
The Commanders are coming off a 24-8 loss against the Philadelphia Eagles.
The Cowboys played the New York Giants on Monday Night Football, winning 23-16.
The Cowboys won both games against the Commanders last season: 27-20 in Week 14 and 56-14 in Week 16.
The NFL Week 4 game is scheduled to kick off at 10 a.m. MST Sunday and can be seen on Fox.
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This article originally appeared on Arizona Republic: Washington Commanders vs. Dallas Cowboys NFL Week 4 game betting odds